Mixed endometrial stromal and smooth muscle tumor

Summary

Mixed endometrial stromal and smooth muscle tumor (MONDO:0004526) is a cancer. A subtype of soft tissue neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	mixed endometrial stromal and smooth muscle tumor
Mondo ID	MONDO:0004526
DOID	DOID:8302
NCIT	C40178, C40179
UMLS	C1513364
MedGen	269077
Anatomy (UBERON)	UBERON:0009853
Is cancer (heuristic)	yes

Also known as: mixed endometrial stromal and smooth muscle neoplasm · Stromomyoma · uterine corpus soft tissue neoplasm

Disease family

This is a subtype of soft tissue neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › connective and soft tissue neoplasm › soft tissue neoplasm › mixed endometrial stromal and smooth muscle tumor

Related subtypes (17): synovium neoplasm, central nervous system mesenchymal non-meningothelial tumor, mediastinal mesenchymal tumor, nodular fasciitis, neoplasm with perivascular epithelioid cell differentiation, desmoid tumor, congenital epulis, inflammatory myofibroblastic tumor, juvenile hyaline fibromatosis, kaposiform hemangioendothelioma, glomus tumor, Mazabraud syndrome, melanoma of soft tissue, malignant soft tissue neoplasm, soft tissue amyloid neoplasm, fibromyxoid tumor, benign soft tissue neoplasm

Subtypes (4): endometrial stromal nodule, uterine corpus perivascular epithelioid cell tumor, uterine corpus rhabdomyosarcoma, leiomyosarcoma of the corpus uteri

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.