MVP1

Summary

MVP1 (MONDO:0024529) is a disease and 2 clinical trials. A subtype of familial mitral valve prolapse — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	MVP1
Mondo ID	MONDO:0024529
OMIM	157700
UMLS	C1834819
MedGen	320443
GARD	0003688
Is cancer (heuristic)	no

Also known as: mitral valve prolapse, familial, X-linked · MVP1 · PMV · prolapsed mitral valve

Disease family

This is a subtype of familial mitral valve prolapse. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › heart disorder › heart valve disorder › mitral valve disorder › mitral valve prolapse › familial mitral valve prolapse › MVP1

Related subtypes (2): mitral valve prolapse, myxomatous 2, mitral valve prolapse, myxomatous 3

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04941456	Not specified	COMPLETED	Does Endurance Improve With the Use of Passy-Muir Valve for Patients With Tracheostomy?
NCT05295381	Not specified	COMPLETED	Abdominal Weight Training Assisted by Cough Assist Machine on Lung Function