myeloid neoplasm associated with PDGFRB rearrangement

Summary

myeloid neoplasm associated with PDGFRB rearrangement (MONDO:0015690) is a cancer. A subtype of myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2 — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	myeloid neoplasm associated with PDGFRB rearrangement
Mondo ID	MONDO:0015690
Orphanet	168950
DOID	DOID:0080166
ICD-11	625932159
NCIT	C84276
SNOMED CT	724642009
UMLS	C3472621
MedGen	758646
GARD	0020107
Is cancer (heuristic)	yes

Also known as: myeloid and lymphoid neoplasms with PDGFRB rearrangement · myeloid neoplasms associated with PDGFRB rearrangement · myeloid neoplasms with PDGFRB rearrangement · myeloid/lymphoid neoplasms with PDGFRB rearrangement

Disease family

This is a subtype of myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › hematopoietic and lymphoid system neoplasm › myeloid hemopathy › myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2 › myeloid neoplasm associated with PDGFRB rearrangement

Related subtypes (3): myeloid neoplasm associated with FGFR1 rearrangement, myeloid neoplasm associated with PDGFRA rearrangement, myeloid/lymphoid neoplasm associated with JAK2 rearrangement

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.