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Atlas / Disease / Myocardial disorder

Myocardial disorder

disease
On this page

Also known as disease of myocardiumdisease or disorder of myocardiumdisorder of myocardiummyocardial diseasemyocardium diseasemyocardium disease or disorder

Summary

Myocardial disorder (MONDO:0024643) is a disease (an umbrella term covering 5 Mondo subtypes) and 23 clinical trials. Top therapeutic interventions include enalapril, atorvastatin, and verapamil. A subtype of heart disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Umbrella term: 5 Mondo subtypes
  • Clinical trials: 23

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

FieldValue
Canonical namemyocardial disorder
Mondo IDMONDO:0024643
NCITC35544
SNOMED CT57809008
UMLSC3241958
MedGen469033
Anatomy (UBERON)UBERON:0002349
Is cancer (heuristic)no

Also known as: disease of myocardium · disease or disorder of myocardium · disorder of myocardium · myocardial disease · myocardial disorder · myocardium disease · myocardium disease or disorder

Disease family

This is a subtype of heart disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › heart disorder › myocardial disorder

Related subtypes (33): endocardium disorder, pericardium disorder, cardiac tuberculosis, heart conduction disease, hypertensive heart disease, heart valve disorder, cardiomyopathy, coronary artery disorder, heart failure, congenital heart disease, heart aneurysm, rheumatic heart disease, cardiac rhythm disease, white forelock with malformations, atrioventricular defect-blepharophimosis-radial and anal defect syndrome, microcephaly-cardiac defect-lung malsegmentation syndrome, PHACE syndrome, microcephaly-facio-cardio-skeletal syndrome, Hadziselimovic type, cardiac anomalies-heterotaxy syndrome, polyvalvular heart disease syndrome, Thomas syndrome, 22q11.2 deletion syndrome, myocardial rupture, heart neoplasm, aortopulmonary window, cor biloculare, inflammation of heart layer, carcinoid heart disease, omphalocele-diaphragmatic hernia-cardiovascular anomalies-radial ray defect syndrome, coronary microvascular disorder, cardiac ventricle disorder, cardiogenetic disease, cardiogenic shock

Subtypes (5): myocarditis, myocardial infarction, conduction system disorder, neoplasm of myocardium, myocardial ischemia

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 23.

Phase distribution (across all retrieved trials)

PhaseTrials
Not specified19
PHASE42
PHASE32

Top trials by phase / activity

NCTPhaseStatusTitle
NCT00348530PHASE4UNKNOWNCarvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic Cardiomyopathy
NCT00701220PHASE4COMPLETEDStatin Therapy for Ischemic and Nonischemic Cardiomyopathy
NCT00000547PHASE3COMPLETEDEnalapril After Anthracycline Cardiotoxicity
NCT00892112PHASE3COMPLETEDIntravenous Immunoglobulin (IVIg) for Parvovirus B19(PVB19) Mediated Cardiomyopathy
NCT05600088Not specifiedACTIVE_NOT_RECRUITINGIntracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina
NCT06697509Not specifiedENROLLING_BY_INVITATIONImproved Detection of Myocardial Fibrosis: a Cardiovascular Magnetic Resonance Imaging Study
NCT06804278Not specifiedRECRUITINGRole of Spectral CT in the Diagnosis of Myocarditis/MINOCA in Patients Undergoing cardioCT Investigations for Acute Chest Pain
NCT06896318Not specifiedACTIVE_NOT_RECRUITINGVirtual Reality-Supported Cardiac Rehabilitation: Psychological, Functional, and Physiological Perspectives
NCT00005227Not specifiedCOMPLETEDAIDS-Associated Cardiomyopathy
NCT00005228Not specifiedCOMPLETEDAIDS-Associated Heart Disease – Incidence and Etiology
NCT00005229Not specifiedCOMPLETEDHIV-Associated Heart Disease
NCT00005251Not specifiedCOMPLETEDGenetic Analysis of Familial Hypertrophic Cardiomyopathy
NCT00005262Not specifiedCOMPLETEDEpidemiology of Idiopathic Dilated Cardiomyopathy (Washington, DC Dilated Cardiomyopathy Study)
NCT00005391Not specifiedCOMPLETEDPediatric Cardiomyopathy Registry
NCT00005455Not specifiedCOMPLETEDChagas Disease as an Undiagnosed Type of Cardiomyopathy in the United States
NCT00326690Not specifiedWITHDRAWNStudy Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity
NCT01815957Not specifiedCOMPLETEDImpact of Ranolazine on Coronary Microcirculatory Resistance
NCT02721693Not specifiedCOMPLETEDTroponin T in Chronic Obstructive Pulmonary Disease (COPD) Patients After Physical Exercise
NCT03488654Not specifiedTERMINATEDCMR-Lupus Comprehensive Approach by Cardiovascular Magnetic Resonance Tomography
NCT04744480Not specifiedCOMPLETEDEffect of Topical Anesthesia on Hemodynamics During the Induction Period in Patients Undergo Cardiac Surgery.
NCT05181254Not specifiedTERMINATEDHEAlth Dialogues for Patients With Mental Illness in Primary Care
NCT05729152Not specifiedUNKNOWNCardiovascular Events for a Long Time End of COVID 19 Infection
NCT07029789Not specifiedCOMPLETEDDeep Learning Super-Resolution Single-Beat CMR

Drugs tested across these trials (top 30)

MoleculeMax phaseTrials referencing
ENALAPRIL43
ATORVASTATIN42
VERAPAMIL41
DEXVERAPAMIL21

About this page

Generated deterministically by Sugi Atlas from primary biomedical databases via BioBTree. Every record on this page traces to a primary source.

Generated
Atlas version
v1.1.4
BioBTree
v2.0.2

Sources 20

This page pulls from 20 datasets indexed by BioBTree:

chembl_moleculecivic_evidenceclinical_trialsclinvarefogenccgwasgwas_studyhgncmedgenmeshmimmondomondochildmondoparentncitorphanetsctiduberonumls