Neoplasm of hypopharynx

Summary

Neoplasm of hypopharynx (MONDO:0021358) is a cancer and 6 clinical trials. A subtype of head and neck neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 6

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	neoplasm of hypopharynx
Mondo ID	MONDO:0021358
NCIT	C3127
SNOMED CT	126686005
UMLS	C0020627
MedGen	43797
Anatomy (UBERON)	UBERON:0001051
Is cancer (heuristic)	yes

Also known as: hypopharyngeal neoplasm · hypopharyngeal neoplasms · hypopharyngeal tumor · hypopharyngeal tumour · hypopharynx neoplasm · hypopharynx neoplasm (disease) · hypopharynx tumor · hypopharynx tumour · neoplasm of hypopharynx · neoplasm of the hypopharynx · tumor of hypopharynx · tumor of the hypopharynx · tumour of hypopharynx · tumour of the hypopharynx

Disease family

This is a subtype of head and neck neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › head and neck neoplasm › neoplasm of hypopharynx

Related subtypes (36): cranial nerve neoplasm, cavernous hemangioma of face, gasserian ganglion meningioma, nasal cavity neoplasm, palatal neoplasm, nasopharyngeal neoplasm, head and neck cancer, head and neck paraganglioma, nasal cavity and paranasal sinus lethal midline granuloma, familial thyroglossal duct cyst, laryngeal neuroendocrine neoplasm, laryngotracheal angioma, facial dermoid cyst, epignathus, nasal glial heterotopia, nasal ganglioglioma, malignant epithelial tumor of salivary glands, benign epithelial tumor of salivary glands, juvenile nasopharyngeal angiofibroma, recurrent respiratory papillomatosis, ocular adnexal lymphoma, gingival neoplasm, odontogenic neoplasm, eye neoplasm, ear neoplasm, tongue neoplasm, buccal mucosa neoplasm, lip neoplasm, tonsil neoplasm, neoplasm of neck, tumor of salivary gland, neoplasm of oropharynx, neoplasm of floor of mouth, lipoma of face, skull neoplasm, nasal cavity and paranasal sinus neoplasm

Subtypes (3): epiglottis neoplasm, hypopharynx cancer, benign neoplasm of hypopharynx

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 6.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	6

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00534729	Not specified	COMPLETED	Organ Preservation: Weekly Carboplatin & Taxol w/Concurrent RT for Locally Advanced Laryngeal & Hypopharyngeal CA
NCT00721539	Not specified	TERMINATED	Assessing the da Vinci® Robotic Surgical System for Surgery of the Upper Aerodigestive Tract
NCT01104714	Not specified	COMPLETED	Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers
NCT02262247	Not specified	COMPLETED	A Post-Market Clinical Trial for Access and Visualization of the Oropharynx, Hypopharynx and Larynx During Transoral Procedures
NCT03010813	Not specified	COMPLETED	A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery
NCT03942380	Not specified	UNKNOWN	Cell-free Tumor DNA in Head and Neck Cancer Patients