Nocturnal paroxysmal dystonia

Summary

Nocturnal paroxysmal dystonia (MONDO:0043969) is a disease. A subtype of dystonic disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	nocturnal paroxysmal dystonia
Mondo ID	MONDO:0043969
MeSH	D020183
SNOMED CT	230500006
UMLS	C0393777
MedGen	95991
GARD	0027970
Is cancer (heuristic)	no

Also known as: dystonia, hypnogenic paroxysmal · dystonia, nocturnal paroxysmal · dystonia, nocturnal, paroxysmal · dystonia, sleep-related · dystonias, hypnogenic paroxysmal · dystonias, nocturnal paroxysmal · dystonias, sleep-related · hypnogenic paroxysmal dystonia · hypnogenic paroxysmal dystonias · nocturnal paroxysmal dystonias · paroxysmal dystonia, hypnogenic · paroxysmal dystonia, nocturnal · paroxysmal dystonias, hypnogenic · paroxysmal dystonias, nocturnal · sleep related dystonia · sleep-related dystonia · sleep-related dystonias

Disease family

This is a subtype of dystonic disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › movement disorder › extrapyramidal and movement disease › dystonic disorder › nocturnal paroxysmal dystonia

Related subtypes (7): focal dystonia, multifocal dystonia, segmental dystonia, hemidystonia-hemiatrophy syndrome, inherited dystonia, idiopathic torsion dystonia, torsion dystonia

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.