Non-functioning pituitary gland neoplasm

Summary

Non-functioning pituitary gland neoplasm (MONDO:0003603) is a cancer and 1 clinical trial. A subtype of pituitary tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	non-functioning pituitary gland neoplasm
Mondo ID	MONDO:0003603
NCIT	C4009
SNOMED CT	448563005
UMLS	C3163649
MedGen	756062
GARD	0023586
Anatomy (UBERON)	UBERON:0000007
Is cancer (heuristic)	yes

Also known as: non-functioning endocrine neoplasm of pituitary gland · non-functioning neoplasm of pituitary · non-functioning neoplasm of pituitary gland · non-functioning neoplasm of the pituitary · non-functioning neoplasm of the pituitary gland · non-functioning pituitary gland neoplasm · non-functioning pituitary gland tumor · non-functioning pituitary gland tumour · non-functioning pituitary neoplasm · non-functioning pituitary tumor · non-functioning pituitary tumour · non-functioning tumor of pituitary · non-functioning tumor of pituitary gland · non-functioning tumor of the pituitary · non-functioning tumor of the pituitary gland · non-functioning tumour of pituitary · non-functioning tumour of pituitary gland · non-functioning tumour of the pituitary · non-functioning tumour of the pituitary gland · nonfunctional pituitary gland neoplasm (+3 more)

Disease family

This is a subtype of pituitary tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › endocrine gland neoplasm › pituitary tumor › non-functioning pituitary gland neoplasm

Related subtypes (8): pituitary cancer, posterior pituitary gland neoplasm, prolactin producing pituitary tumor, functioning pituitary gland neoplasm, pituitary gland adenoma, growth hormone-producing pituitary gland neoplasm, benign neoplasm of pituitary gland, ACTH-producing pituitary gland neoplasm

Subtypes (1): non-functioning pituitary adenoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01568359	Not specified	COMPLETED	Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary Tumors