Orbit neoplasm

Summary

Orbit neoplasm (MONDO:0024611) is a cancer and 11 clinical trials. A subtype of disorder of orbital region — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 11

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	orbit neoplasm
Mondo ID	MONDO:0024611
NCIT	C3290
UMLS	C0029185
MedGen	18190
GARD	0025436
Anatomy (UBERON)	UBERON:0001697
Is cancer (heuristic)	yes

Also known as: neoplasm of orbit · neoplasm of orbit of skull · neoplasm of the orbit · orbit neoplasm · orbit of skull neoplasm · orbit of skull tumor · orbit of skull tumour · orbit tumor · orbit tumour · orbital neoplasm · orbital neoplasms · orbital tumor · orbital tumour · tumor of orbit · tumor of orbit of skull · tumor of the orbit · tumour of orbit · tumour of orbit of skull · tumour of the orbit

Disease family

This is a subtype of disorder of orbital region. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › disorder of orbital region › orbit neoplasm

Related subtypes (3): eye adnexa disorder, eye disorder, orbital dermoid cyst

Subtypes (2): intraorbital meningioma, orbital cancer

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 11.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	11

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06791226	Not specified	RECRUITING	Evaluating the Usefulness of 18F-AlF-FAPI PET/ CT in Orbital Neoplasms
NCT01884207	Not specified	COMPLETED	Multiparametric Characterization of Orbital Tumors by MRI
NCT02401906	Not specified	COMPLETED	MRI and Orbital Tumours (MEDORT)
NCT02434120	Not specified	COMPLETED	MRI Perfusion Curves Typology and Orbital Tumors (PERFORM)
NCT02678091	Not specified	COMPLETED	Ultrasound Exam With Doppler for the Etiological Diagnosis of Orbital Masses (PUCE)
NCT03195101	Not specified	UNKNOWN	Evaluation of Transconjunctival Approach in Management of Orbital Tumors
NCT04704414	Not specified	UNKNOWN	Exophthalmometry With 3D Face Scanners
NCT05438784	Not specified	UNKNOWN	Application of CAD-CAM Technology in Orbital Bone Reconstruction
NCT05613244	Not specified	COMPLETED	Descriptive Study of a Cohort of Orbital Solitary Fibrous Tumors
NCT05645341	Not specified	COMPLETED	Artificial Intelligence-assisted Screening of Malignant Pigmented Tumors on the Ocular Surface
NCT06336499	Not specified	COMPLETED	Risk Stratification of Orbital Tumors Based on MRl and Artificial Intelligence