Osteochondrosis

Summary

Osteochondrosis (MONDO:0018381) is a disease (an umbrella term covering 11 Mondo subtypes) and 1 clinical trial. A subtype of osteonecrosis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Umbrella term: 11 Mondo subtypes
• Clinical trials: 1

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	osteochondrosis
Mondo ID	MONDO:0018381
MeSH	D055034
Orphanet	399319
DOID	DOID:8125
ICD-10-CM	M42
ICD-11	1446309782
NCIT	C34879
SNOMED CT	19579005
UMLS	C0029429
MedGen	18216
GARD	0012704
Is cancer (heuristic)	no

Also known as: osteochondrosis not specified as adult or juvenile, of unspecified site

Disease family

This is a subtype of osteonecrosis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › skeletal system disorder › bone disorder › osteonecrosis › osteochondrosis

Related subtypes (6): Kummell disease, avascular necrosis, osteonecrosis of genetic origin, idiopathic phalangeal acro-osteolysis, Dieterich disease, osteoradionecrosis

Subtypes (11): Osgood-Schlatter disease, Legg-Calve-Perthes disease, Thiemann disease, familial form, Scheuermann disease, dihydropyrimidine dehydrogenase deficiency, osteochondritis of tarsal/metatarsal bone, medial condensing osteitis of the clavicle, Kienbock disease, panner disease, Sinding-Larsen-Johansson disease, Freiberg disease

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 1.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05846477	Not specified	UNKNOWN	MySpine MC Versus MySpine Standard