Otorhinolaryngologic disease
disease diseaseOn this page
Also known as disease, ENTdisease, otolaryngologicdisease, otolaryngologicaldisease, otorhinolaryngologicdisease, otorhinolaryngologicaldiseases, ENTdiseases, otolaryngologicdiseases, otolaryngologicaldiseases, otorhinolaryngologicdiseases, otorhinolaryngologicalear, nose and throat disorderear, nose or throat disorderear/nose/throat diseaseENT diseaseENT diseasesotolaryngologic diseaseotolaryngologic diseasesotolaryngologic disorderotolaryngological diseaseotolaryngological diseases
Summary
Otorhinolaryngologic disease (MONDO:0024623) is a disease (an umbrella term covering 40 Mondo subtypes) and 49 clinical trials. Top therapeutic interventions include ciprofloxacin. A subtype of disease by body system or component — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Umbrella term: 40 Mondo subtypes
- Clinical trials: 49
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | otorhinolaryngologic disease |
| Mondo ID | MONDO:0024623 |
| MeSH | D010038 |
| NCIT | C118420 |
| SNOMED CT | 232208008 |
| UMLS | C0395797 |
| MedGen | 583054 |
| Anatomy (UBERON) | UBERON:0007811 |
| Is cancer (heuristic) | no |
Also known as: disease, ENT · disease, otolaryngologic · disease, otolaryngological · disease, otorhinolaryngologic · disease, otorhinolaryngological · diseases, ENT · diseases, otolaryngologic · diseases, otolaryngological · diseases, otorhinolaryngologic · diseases, otorhinolaryngological · ear, nose and throat disorder · ear, nose or throat disorder · ear/nose/throat disease · ENT disease · ENT diseases · otolaryngologic disease · otolaryngologic diseases · otolaryngologic disorder · otolaryngological disease · otolaryngological diseases (+3 more)
Disease family
An umbrella term covering 40 Mondo subtypes.
Classification path: disease › human disease › disease by body system or component › otorhinolaryngologic disease
Related subtypes (18): disorder of orbital region, integumentary system disorder, musculoskeletal system disorder, urinary system disorder, syndromic disease, auditory system disorder, breast disorder, connective tissue disorder, digestive system disorder, cardiovascular disorder, reproductive system disorder, immune system disorder, nervous system disorder, respiratory system disorder, endocrine system disorder, hematologic disorder, mouth disorder, disorder of visual system
Subtypes (40): bifid nose, autoimmune disease of ear, nose and throat, nasal disorder, atresia of external auditory canal and conductive deafness, external auditory canal atresia-vertical talus-hypertelorism syndrome, laryngeal abductor paralysis, larynx atresia, congenital velopharyngeal incompetence, microtia, congenital tracheal stenosis, laryngeal neuroendocrine neoplasm, arrhinia, laryngotracheal angioma, epignathus, nasolacrimal duct cyst, polyrrhinia, supernumerary nostril, proboscis lateralis, nasal glial heterotopia, nasal ganglioglioma, nasal encephalocele, isolated congenital syngnathia, cysts and fistulae of the face and oral cavity, isolated congenital nasal pyriform aperture stenosis, congenital nasal pyriform aperture stenosis with holoprosencephaly, middle ear anomaly, idiopathic bilateral vestibulopathy, mal de Debarquement, juvenile nasopharyngeal angiofibroma, tracheal agenesis, semicircular canal dehiscence syndrome, hereditary otorhinolaryngologic disease, supratip dysplasia, recurrent respiratory papillomatosis, silent sinus syndrome, anotia, congenital tracheomalacia, disorder of pharynx, disorder of ear, lip and oral cavity squamous cell carcinoma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 49.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 42 |
| PHASE2 | 3 |
| PHASE4 | 2 |
| PHASE1/PHASE2 | 2 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03783702 | PHASE4 | COMPLETED | Pain Control Following Sinus Surgery |
| NCT04213508 | PHASE4 | UNKNOWN | Type and Frequency of Nasal Irrigation in Rhinosinusitis Patients |
| NCT06370351 | PHASE1/PHASE2 | RECRUITING | A Phase I/II Clinical Trial with SENS-501 in Children Suffering from Severe to Profound Hearing Loss Due to Otoferlin (OTOF) Mutations |
| NCT00213837 | PHASE2 | COMPLETED | Reconstruction Implant Bone After Removal Using Porous Titanium Prosthesis |
| NCT00872209 | PHASE1/PHASE2 | COMPLETED | Safety and Efficacy Study of Foam Otic Cipro Compared to a Standard Solution ( Ciloxan - Alcon Labs ) to Treat Acute Otitis Externa |
| NCT01157819 | PHASE2 | COMPLETED | Safety and Efficacy of Once-Daily Dosing of FoamOtic Cipro Compared to Twice-Daily Dosing of Ciloxan Ear Drops in Patients With Acute External Otitis |
| NCT01359098 | PHASE2 | COMPLETED | Efficacy and Safety of Once-Daily Ciprodexa Otic Foam Compared to Twice-daily Ciprodex Ear Drops in Acute Otitis Externa |
| NCT01524276 | Not specified | RECRUITING | Product Surveillance Registry |
| NCT04124198 | Not specified | ACTIVE_NOT_RECRUITING | Quality of Life After Primary TORS vs IMRT for Patients With Early-stage Oropharyngeal Squamous Cell Carcinoma |
| NCT04547673 | Not specified | RECRUITING | To Develop and Validate a Nasoendoscopic Intelligent Diagnostic System for Nasopharyngeal Carcinoma |
| NCT05859568 | Not specified | ENROLLING_BY_INVITATION | Baseline Performance and Fitting Parameters for Sonova Products |
| NCT06051968 | Not specified | ACTIVE_NOT_RECRUITING | Effects of an Online Hearing Support for First-time Hearing Aid Users |
| NCT06258837 | Not specified | RECRUITING | Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils |
| NCT06464757 | Not specified | RECRUITING | Laryngomalacia, Examinations and Quality of Life in Children Before and After Treatment With Follow-up After 1 Year |
| NCT06478433 | Not specified | NOT_YET_RECRUITING | Study on the Efficacy and Safety of a Device for Post-op Recovery in Pediatric Adenectomy/Adenotonsillectomy. |
| NCT07435870 | Not specified | NOT_YET_RECRUITING | Analgesia Nociception Index Monitoring in Trigeminal Cardiac Reflex During Nasal Septoplasty |
| NCT00001167 | Not specified | COMPLETED | Ultrasound Evaluation of Tongue Movements in Speech and Swallowing |
| NCT00948779 | Not specified | COMPLETED | Antibiotic Education for Children in an Emergency Care Unit |
| NCT01483937 | Not specified | COMPLETED | Evaluation of a Sensory Enrichment Multimodal Device (SEMD) on Physical Therapy Patients With Disequilibrium |
| NCT01669278 | Not specified | WITHDRAWN | Evaluation of Office-Based Sheathed Flexible Nasopharyngoscopy |
| NCT01738490 | Not specified | COMPLETED | Long-term Stability and Survival Rates of a Novel Oticon Medical Bone Conduction Device Implant |
| NCT01959152 | Not specified | TERMINATED | Evaluation of Hearing Preservation in Adults With Partial Low-Frequency Hearing Implanted With the HiFocus™ Mid-Scala Electrode |
| NCT02189798 | Not specified | TERMINATED | Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults With Partial Deafness |
| NCT02315911 | Not specified | COMPLETED | Randomized Control Trials of Surgery for Pediatric OSA |
| NCT02453633 | Not specified | UNKNOWN | Theory Based SMS Reminders - Text’s Impact on Patient Attendance |
| NCT02751658 | Not specified | COMPLETED | Tap to Tap, Pathobiome Associates Health Care |
| NCT02811549 | Not specified | COMPLETED | Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss |
| NCT02927652 | Not specified | COMPLETED | Psychiatric Comorbidity |
| NCT02965183 | Not specified | UNKNOWN | The Correlation Between Adenoid Hypertrophy and Body Temperature in Children Before and After Adenoidectomy |
| NCT03010813 | Not specified | COMPLETED | A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery |
| NCT03167463 | Not specified | UNKNOWN | Stentless Endoscopic Transnasal Transseptal Choanoplasty |
| NCT03243344 | Not specified | COMPLETED | Randomized Assessment of Devices Used to Prevent Post-operative Hemorrhagic Risk in Endonasal Surgery |
| NCT03501641 | Not specified | COMPLETED | Heart Rate Variability and Cognitive Load on Image-Based Virtual Reality Instructional Design in Otolaryngology |
| NCT03695666 | Not specified | COMPLETED | A Completed-cycle Local Audit of Patient Load in the SHO-led ENT Casualty Clinic |
| NCT03793816 | Not specified | COMPLETED | Tonsillectomy Using BiZact™ - a Randomized Side-controlled Clinical Trial |
| NCT03931226 | Not specified | COMPLETED | Impact of Spa Treatments on the Consumption of Care in Children |
| NCT04151264 | Not specified | COMPLETED | Influence of the Hypotension Probability Index on Intraoperative and Postoperative Hypotension in ENT- and OM-Surgery |
| NCT04162405 | Not specified | UNKNOWN | Tinnitus in Patients With and Without Sensorineural Hearing Loss |
| NCT04237207 | Not specified | COMPLETED | Clinical Evaluation of a Cochlear Implant Sound Processor |
| NCT04464304 | Not specified | COMPLETED | Virtual Reality for Postoperative Pain Management |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| CIPROFLOXACIN | 4 | 3 |
Related Atlas pages
- Drugs: Ciprofloxacin