Ovarian epithelial tumor

Summary

Ovarian epithelial tumor (MONDO:0002229) is a cancer (an umbrella term covering 11 Mondo subtypes) and 2 clinical trials. Top therapeutic interventions include veliparib. A subtype of epithelial neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Umbrella term: 11 Mondo subtypes
• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	ovarian epithelial tumor
Mondo ID	MONDO:0002229
DOID	DOID:2152
NCIT	C4381
SNOMED CT	237057005
UMLS	C0341823
MedGen	90969
Anatomy (UBERON)	UBERON:0000992
Is cancer (heuristic)	yes

Also known as: epithelial neoplasm of ovary · epithelial neoplasm of the ovary · epithelial tumor of ovary · epithelial tumor of the ovary · epithelial tumour of ovary · epithelial tumour of the ovary · ovarian epithelial tumor · ovarian surface epithelial-stromal tumor · ovarian surface epithelial-stromal tumour · ovarian surface-epithelial stromal neoplasm · ovary epithelial neoplasm · OVT

Data availability: 54 intOGen driver records.

Disease family

An umbrella term covering 11 Mondo subtypes.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › epithelial neoplasm › ovarian epithelial tumor

Related subtypes (23): myoepithelial tumor, endometrioid tumor, squamous cell neoplasm, pancreatic delta cell neuroendocrine tumor, thyroid hyalinizing trabecular adenoma, Wolffian adnexal tumor, adenoma, carcinoma, cystic, mucinous, and serous neoplasm, thymic epithelial neoplasm, epithelial tumor of anal canal, growth hormone-producing pituitary gland neoplasm, basal cell neoplasm, sympathetic paraganglioma, papillary epithelial neoplasm, epithelial skin neoplasm, glandular cell neoplasm, intraepithelial neoplasia, epithelial neoplasm of rectum, epithelial tumor of colon, mesonephric neoplasm, benign epithelial neoplasm, transitional cell neoplasm

Subtypes (11): ovarian Brenner tumor, ovarian squamous cell neoplasm, ovarian mucinous neoplasm, ovarian seromucinous tumor, ovarian papillary tumor, ovarian mucinous adenofibroma, ovarian adenoma benign, borderline epithelial tumor of ovary, malignant epithelial tumor of ovary, ovarian clear cell tumor, ovarian serous tumor

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE2	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04519151	PHASE2	RECRUITING	Pembrolizumab and Lenvatinib for Platinum- Sensitive Recurrent Ovarian Cancer
NCT01540565	PHASE2	COMPLETED	Veliparib in Treating Patients With Persistent or Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
VELIPARIB	3	2