Ovarian fibroma

Summary

Ovarian fibroma (MONDO:0008168) is a disease. A subtype of ovarian benign neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Prevalence: Unknown (Worldwide)
• Phenotypes (HPO): 11

Clinical features

Signs & symptoms

Clinical features (HPO)

11 HPO clinical features (Orphanet curated; top 11 by frequency):

HPO ID	Term	Frequency
HP:0000137	Abnormality of the ovary	Very frequent (80-99%)
HP:0002027	Abdominal pain	Very frequent (80-99%)
HP:0002202	Pleural effusion	Very frequent (80-99%)
HP:0003270	Abdominal distention	Very frequent (80-99%)
HP:0010618	Ovarian fibroma	Very frequent (80-99%)
HP:0001541	Ascites	Frequent (30-79%)
HP:0002586	Peritonitis	Frequent (30-79%)
HP:0002671	Basal cell carcinoma	Frequent (30-79%)
HP:0008703	Gonadal calcification	Frequent (30-79%)
HP:0010603	Odontogenic keratocysts of the jaw	Frequent (30-79%)
HP:0030451	Mesenteric cyst	Frequent (30-79%)

Identifiers

Disease identifiers

Field	Value
Canonical name	ovarian fibroma
Mondo ID	MONDO:0008168
MeSH	C562391
OMIM	166970
Orphanet	314473
ICD-11	871413134
NCIT	C3498
SNOMED CT	254865006
UMLS	C0149951
MedGen	57706
GARD	0021375
MedDRA	10064257
Is cancer (heuristic)	no

Also known as: fibroma of ovary · fibroma of the ovary · ovarian fibroma · ovarian fibroma (disease)

Data availability: 1 HPO phenotype.

Disease family

This is a subtype of ovarian benign neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › benign neoplasm › benign reproductive system neoplasm › benign female reproductive system neoplasm › ovarian benign neoplasm › ovarian fibroma

Related subtypes (14): benign struma ovarii, ovarian endometrioid adenofibroma, ovarian clear cell adenofibroma, ovarian surface papilloma, ovarian mucinous adenofibroma, rete ovarii cystadenofibroma, ovarian adenoma benign, ovarian serous adenofibroma, serous or mucinous cystadenoma of childhood, Meigs syndrome, pseudo-Meigs syndrome, atypical Meigs syndrome, benign ovarian sex cord-stromal tumor, benign ovarian mucinous tumor

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.