Pancreatic intraductal papillary-mucinous carcinoma

Summary

Pancreatic intraductal papillary-mucinous carcinoma (MONDO:0004285) is a cancer. A subtype of exocrine pancreatic carcinoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Prevalence: <1 / 1 000 000 (Europe) [Orphanet-validated]

Clinical features

Epidemiology

Prevalence records

13 prevalence record(s), Orphanet:

Type	Class	Value	Geography	Validation
Annual incidence	<1 / 1 000 000	0.011	Europe	Validated
Annual incidence	<1 / 1 000 000	0.017	Belgium	Validated
Annual incidence	<1 / 1 000 000	0.028	Czech Republic	Validated
Annual incidence	<1 / 1 000 000	0.031	France	Validated
Annual incidence	<1 / 1 000 000	0.048	Germany	Validated
Annual incidence	<1 / 1 000 000	0.006	Ireland	Validated
Annual incidence	<1 / 1 000 000	0.006	Italy	Validated
Annual incidence	<1 / 1 000 000	0.041	Norway	Validated
Annual incidence	<1 / 1 000 000	0.006	Portugal	Validated
Annual incidence	<1 / 1 000 000	0.018	Spain	Validated
Annual incidence	<1 / 1 000 000	0.028	Switzerland	Validated
Annual incidence	<1 / 1 000 000	0.016	Netherlands	Validated
Annual incidence	<1 / 1 000 000	0.001	United Kingdom	Validated

Identifiers

Disease identifiers

Field	Value
Canonical name	pancreatic intraductal papillary-mucinous carcinoma
Mondo ID	MONDO:0004285
Orphanet	424058
DOID	DOID:7574
ICD-11	2086328209
NCIT	C5725
UMLS	C1335304
MedGen	235451
GARD	0021779
Is cancer (heuristic)	yes

Also known as: intraductal papillary mucinous carcinoma of pancreas · intraductal papillary-mucinous carcinoma of pancreas · pancreatic intraductal papillary mucinous carcinoma · pancreatic intraductal papillary-mucinous carcinoma

Data availability: 1 cell line.

Disease family

This is a subtype of exocrine pancreatic carcinoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › digestive system cancer › malignant pancreatic neoplasm › malignant exocrine pancreas neoplasm › exocrine pancreatic carcinoma › pancreatic intraductal papillary-mucinous carcinoma

Related subtypes (7): pancreatic adenocarcinoma, pancreatic large cell neuroendocrine carcinoma, familial pancreatic carcinoma, squamous cell carcinoma of pancreas, pancreatic mucinous cystadenoma, solid pseudopapillary carcinoma of pancreas, pancreatic carcinoma with mixed differentiation

Subtypes (2): pancreatic intraductal papillary-mucinous neoplasm with high grade dysplasia, pancreatic intraductal papillary-mucinous neoplasm with an associated invasive carcinoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.