papillary thyroid Microcarcinoma
disease diseaseOn this page
Also known as papillary Microcarcinoma of the thyroidpapillary Microcarcinoma of the thyroid glandpapillary thyroid gland Microcarcinomathyroid gland papillary Microcarcinoma
Summary
papillary thyroid Microcarcinoma (MONDO:0011368) is a disease and 21 clinical trials. Top therapeutic interventions include thyroid. A subtype of familial papillary or follicular thyroid carcinoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 21
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | papillary thyroid Microcarcinoma |
| Mondo ID | MONDO:0011368 |
| MeSH | C563277 |
| OMIM | 603744 |
| NCIT | C46004 |
| UMLS | C1709457 |
| MedGen | 313563 |
| GARD | 0015358 |
| Is cancer (heuristic) | no |
Also known as: papillary Microcarcinoma of the thyroid · papillary Microcarcinoma of the thyroid gland · papillary thyroid gland Microcarcinoma · papillary thyroid Microcarcinoma · thyroid gland papillary Microcarcinoma
Disease family
Classification path: disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › endocrine gland neoplasm › thyroid tumor › thyroid cancer › thyroid gland carcinoma › differentiated thyroid carcinoma › familial papillary or follicular thyroid carcinoma › papillary thyroid Microcarcinoma
Related subtypes (5): thyroid cancer, nonmedullary, 2, thyroid carcinoma, nonmedullary, with or without cell oxyphilia, thyroid cancer, nonmedullary, 3, thyroid cancer, nonmedullary, 4, thyroid cancer, nonmedullary, 5
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 21.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 20 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT04623801 | PHASE2 | ACTIVE_NOT_RECRUITING | Laser Ablation of Papillary Thyroid Microcarcinoma |
| NCT02609685 | Not specified | RECRUITING | Active Surveillance of Papillary Thyroid Microcarcinoma |
| NCT02938702 | Not specified | ACTIVE_NOT_RECRUITING | Active Surveillance on Papillary Thyroid Microcarcinoma |
| NCT04624477 | Not specified | ACTIVE_NOT_RECRUITING | Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer |
| NCT05189821 | Not specified | RECRUITING | RFA Treatment for Papillary Thyroid Microcarcinoma |
| NCT06333587 | Not specified | RECRUITING | Minimally Invasive Treatments of the Thyroid |
| NCT07054229 | Not specified | RECRUITING | Efficacy and Prognosis of Microwave Ablation Treatment for Papillary Thyroid Microcarcinoma Assessed by Contrast-Enhanced Ultrasound Combined With Genetic and Molecular Diagnostics: A Prospective Observational Study |
| NCT07249125 | Not specified | NOT_YET_RECRUITING | Safety and Quality of Life of Three Treatment Strategies for Low-Risk Papillary Thyroid Microcarcinoma |
| NCT07536412 | Not specified | NOT_YET_RECRUITING | Decision Aid Efficacy in Low Risk Thyroid Cancer |
| NCT01384669 | Not specified | COMPLETED | Genetic Expression Alteration Affect on Lateral Neck Node Metastasis of Thyroid Papillary Microcarcinoma : Microarray Analysis |
| NCT01648569 | Not specified | COMPLETED | Long-term Outcomes of Total Thyroidectomy Versus Less Than Total Thyroidectomy for Papillary Thyroid Microcarcinoma |
| NCT03327636 | Not specified | SUSPENDED | A Trial Comparing USG-HIFU vs AS in Management of Low-risk PTMC |
| NCT03432299 | Not specified | UNKNOWN | Radiofrequency Ablation of Low Risk Papillary Thyroid Microcarcinoma |
| NCT03808779 | Not specified | UNKNOWN | A Multicenter Trial of Radiofrequency Ablation vs. Surgery as Treatment of Papillary Thyroid Microcarcinoma. |
| NCT04129281 | Not specified | UNKNOWN | Active Surveillance Versus Surgery in Thyroid Papillary Microcarcinoma |
| NCT04129411 | Not specified | COMPLETED | Treatment of Papillary Thyroid Carcinoma With Radiofrequency Ablation |
| NCT04376203 | Not specified | UNKNOWN | Microbiome and Papillary Thyroid Microcarcinoma |
| NCT06583057 | Not specified | COMPLETED | Multicenter Comparison of Thermal Ablation Versus Thyroid Lobectomy for Subcapsular Papillary Thyroid Microcarcinoma |
| NCT06871956 | Not specified | COMPLETED | PMRA and Shapley-Based Machine Learning for Predicting Lymph Node Metastasis in Central Subregions of Clinically Node-Negative Papillary Thyroid Microcarcinoma: a Prospective Multicenter Validation and Development of a Web Calculator |
| NCT07107503 | Not specified | COMPLETED | 10 Years’ Follow-up Results of Ultrasound-guided Radiofrequency Ablation Versus Surgery for Low-risk Papillary Thyroid Micro-carcinoma |
| NCT07506161 | Not specified | COMPLETED | Radiofrequency Ablation Treatment of Low-Risk Papillary Thyroid Carcinomas |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| THYROID | 3 | 1 |
Related Atlas pages
- Drugs: Thyroid