Paranasal sinus cancer
diseaseOn this page
Also known as malignant accessory sinus neoplasmmalignant accessory sinus tumormalignant accessory sinus tumourmalignant neoplasm of accessory sinusmalignant neoplasm of paranasal sinusmalignant neoplasm of the accessory sinusmalignant neoplasm of the paranasal sinusmalignant paranasal sinus neoplasmmalignant paranasal sinus tumormalignant paranasal sinus tumourmalignant tumor of accessory sinusmalignant tumor of paranasal sinusmalignant tumor of the accessory sinusmalignant tumor of the paranasal sinusmalignant tumour of accessory sinusmalignant tumour of paranasal sinusmalignant tumour of the accessory sinusmalignant tumour of the paranasal sinus
Summary
Paranasal sinus cancer (MONDO:0020669) is a cancer and 6 clinical trials. Top therapeutic interventions include cisplatin. A subtype of respiratory system cancer — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 6
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | paranasal sinus cancer |
| Mondo ID | MONDO:0020669 |
| NCIT | C7487 |
| UMLS | C0153474 |
| MedGen | 56305 |
| GARD | 0025207 |
| Anatomy (UBERON) | UBERON:0001825 |
| Is cancer (heuristic) | yes |
Also known as: malignant accessory sinus neoplasm · malignant accessory sinus tumor · malignant accessory sinus tumour · malignant neoplasm of accessory sinus · malignant neoplasm of paranasal sinus · malignant neoplasm of the accessory sinus · malignant neoplasm of the paranasal sinus · malignant paranasal sinus neoplasm · malignant paranasal sinus tumor · malignant paranasal sinus tumour · malignant tumor of accessory sinus · malignant tumor of paranasal sinus · malignant tumor of the accessory sinus · malignant tumor of the paranasal sinus · malignant tumour of accessory sinus · malignant tumour of paranasal sinus · malignant tumour of the accessory sinus · malignant tumour of the paranasal sinus
Disease family
This is a subtype of respiratory system cancer. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › respiratory system cancer › paranasal sinus cancer
Related subtypes (8): nasal cavity cancer, tracheal cancer, bronchus cancer, larynx cancer, pharynx cancer, pleural cancer, lung cancer, SMARCA4-deficient sarcoma of thorax
Subtypes (2): paranasal sinus carcinoma, paranasal sinus lymphoma
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 6.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| PHASE2 | 3 |
| Not specified | 3 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03096808 | PHASE2 | COMPLETED | Adaptive Radiotherapy for Head and Neck Cancer |
| NCT03274414 | PHASE2 | COMPLETED | A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages |
| NCT05114707 | PHASE2 | UNKNOWN | Camrelizumab Plus Chemoradiotherapy for Patients With Locoregional Cancer of Nasal Cavity and Paranasal Sinuses |
| NCT02012699 | Not specified | RECRUITING | Integrated Cancer Repository for Cancer Research |
| NCT05614375 | Not specified | RECRUITING | Endoscopic Surgery in the Treatment of Soft Tissue Sarcoma in Nasal and Paranasal Sinus |
| NCT03049358 | Not specified | TERMINATED | Olfactory Training in Improving Sense of Smell After Radiation Therapy in Patients With Paranasal Sinus or Nasopharyngeal Cancer |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| CISPLATIN | 4 | 1 |
Related Atlas pages
- Drugs: Cisplatin