Parotid gland neoplasm
disease diseaseOn this page
Also known as neoplasm of parotidneoplasm of parotid glandneoplasm of the parotidneoplasm of the parotid glandparotid gland neoplasm (disease)parotid gland tumorparotid gland tumourparotid neoplasmparotid tumorparotid tumourtumor of parotidtumor of parotid glandtumor of the parotidtumor of the parotid glandtumour of parotidtumour of parotid glandtumour of the parotidtumour of the parotid gland
Summary
Parotid gland neoplasm (MONDO:0021243) is a cancer and 21 clinical trials. Top therapeutic interventions include citric acid, gadobutrol, and bevonescein. A subtype of parotid disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 21
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | parotid gland neoplasm |
| Mondo ID | MONDO:0021243 |
| EFO | EFO:0003873 |
| NCIT | C3314 |
| SNOMED CT | 126788000 |
| UMLS | C0030581 |
| MedGen | 18313 |
| Anatomy (UBERON) | UBERON:0001831 |
| Is cancer (heuristic) | yes |
Also known as: neoplasm of parotid · neoplasm of parotid gland · neoplasm of the parotid · neoplasm of the parotid gland · parotid gland neoplasm (disease) · parotid gland tumor · parotid gland tumour · parotid neoplasm · parotid tumor · parotid tumour · tumor of parotid · tumor of parotid gland · tumor of the parotid · tumor of the parotid gland · tumour of parotid · tumour of parotid gland · tumour of the parotid · tumour of the parotid gland
Disease family
An umbrella term covering 2 Mondo subtypes.
Classification path: disease › human disease › disease by body system or component › mouth disorder › salivary gland disorder › parotid disorder › parotid gland neoplasm
Related subtypes (1): parotitis
Subtypes (2): parotid gland cancer, benign neoplasm of parotid gland
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 21.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 17 |
| EARLY_PHASE1 | 2 |
| PHASE3 | 1 |
| PHASE1/PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01414790 | PHASE3 | COMPLETED | The Use of Human Acellular Dermal Matrix to Improve Infraauricular Depressed Deformities and Frey’s Syndrome |
| NCT04420689 | PHASE1/PHASE2 | COMPLETED | Bevonescein to Highlight Nerves in Patients Undergoing Head & Neck Surgery |
| NCT00534612 | EARLY_PHASE1 | UNKNOWN | Diagnostic Accuracy of Fine Needle Aspiration in Parotid Tumors |
| NCT04296266 | EARLY_PHASE1 | COMPLETED | Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery |
| NCT04613349 | Not specified | RECRUITING | FArial NErf MRI in the Preoperative Assessment of PArotide Tumors |
| NCT05296109 | Not specified | RECRUITING | Application of 3D MR Neurogram for Intraparotid Facial Nerves Evaluation |
| NCT07523373 | Not specified | NOT_YET_RECRUITING | Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch |
| NCT01983176 | Not specified | COMPLETED | Retrospective Clinical Outcome of Parotid Tumor Surgery |
| NCT02294838 | Not specified | UNKNOWN | Feasibility Study of MRI Imaging on Parotid Gland Stimulation |
| NCT02527226 | Not specified | COMPLETED | Post-parotidectomy Facial Paresis: Intraoperative and Postoperative Factors |
| NCT03822728 | Not specified | COMPLETED | Intra-parotid Facial Nerve Imaging in Parotidectomy |
| NCT03849482 | Not specified | UNKNOWN | Multiparametric Magnetic Resonance Imaging Versus Fine Needle Aspiration Cytology for Parotid Gland Neoplasms |
| NCT03950323 | Not specified | UNKNOWN | Intra-parotid Facial Nerve Tractography |
| NCT04028479 | Not specified | COMPLETED | The Registry of Oncology Outcomes Associated With Testing and Treatment |
| NCT04104802 | Not specified | WITHDRAWN | Study of the Facial Nerve in MRI 3T in the Preoperative Assessment of Parotid Tumors |
| NCT04803032 | Not specified | COMPLETED | Trident Landmark as a Safe and Easy Method for Facial Nerve Trunk Identification During Superficial Parotidectomy |
| NCT05152056 | Not specified | COMPLETED | MRI and Fine Needle Aspiration in the Diagnosis of Parotid Tumors |
| NCT05401370 | Not specified | UNKNOWN | Role of Methylene Blue in Parotid Surgery |
| NCT05505318 | Not specified | UNKNOWN | Pattern and Surgical Treatment of Parotid Gland Neoplasms |
| NCT05738395 | Not specified | UNKNOWN | Symptoms of Frey’s Syndrome |
| NCT07185542 | Not specified | COMPLETED | Function-Preserving Surgery for Parotid Tumors: Intracapsular Versus Superficial Parotidectomy; A Randomized Clinical Trial. |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| CITRIC ACID | 4 | 1 |
| GADOBUTROL | 4 | 1 |
| BEVONESCEIN | 3 | 1 |
Related Atlas pages
- Drugs: Citric Acid, Gadobutrol, Bevonescein