Patellar tendinitis
diseaseOn this page
Also known as patella tendinitispatellar tendonitistendinitis of patella
Summary
Patellar tendinitis (MONDO:0001042) is a disease with 1 GWAS associations across 1 studies and 16 clinical trials. A subtype of tendinitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- GWAS associations: 1
- Clinical trials: 16
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | patellar tendinitis |
| Mondo ID | MONDO:0001042 |
| DOID | DOID:10471 |
| ICD-10-CM | M76.5 |
| ICD-11 | 1366847963 |
| SNOMED CT | 37785001 |
| UMLS | C0158317 |
| MedGen | 510513 |
| Anatomy (UBERON) | UBERON:0002446 |
| Is cancer (heuristic) | no |
Also known as: patella tendinitis · patellar tendonitis · tendinitis of patella
Data availability: 1 GWAS association (1 study).
Disease family
This is a subtype of tendinitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › muscle tissue disorder › skeletal muscle disorder › myopathy › myositis disease › tendinitis › patellar tendinitis
Related subtypes (5): tibialis tendinitis, Achilles bursitis, calcific tendinitis, tenosynovitis, paratenonitis
Genetics & variants
GWAS landscape
1 GWAS associations across 1 studies. Top hits map to 2 distinct genes (as reported by GWAS).
Top associations by p-value
| rsID | p-value | Gene | Risk allele | Odds ratio |
|---|---|---|---|---|
| rs149047058 | 2e-11 | COA1, STK17A | A | 2.75 |
Top studies (by case count)
| Study | Lead author | Year | Cases | Controls | Title |
|---|---|---|---|---|---|
| GCST90054797 | Kim SK | 2021 | 1,670 | 293,866 | Association of COA1 with Patellar Tendonitis: A Genome-wide Association Analysis. |
Variant details and genetic-evidence tiers
Tier distribution (top 50 variants)
| Tier | Variants |
|---|---|
| Tier 1: coding | 0 |
| Tier 2: splice/UTR | 0 |
| Tier 3: regulatory | 0 |
| Tier 4: intronic/intergenic | 1 |
MAF distribution
| Bucket | Variants |
|---|---|
| common (>=0.05) | 0 |
| low_freq (0.01-0.05) | 0 |
| rare (<0.01) | 1 |
| unknown | 0 |
Functional consequences
| Consequence | Count |
|---|---|
| intron_variant | 1 |
Top variants
| rsID | Chr | Pos | Alleles | MAF | Consequence | Gene | p-value | Tier |
|---|---|---|---|---|---|---|---|---|
| rs149047058 | 7 | 43642040 | G>A | 0.009 | intron_variant | COA1, STK17A | 2e-11 | Tier 4: intronic/intergenic |
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 16.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 15 |
| PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03136965 | PHASE2 | COMPLETED | Platelet-Rich Plasma Therapy for Patellar Tendinopathy |
| NCT07406516 | Not specified | NOT_YET_RECRUITING | Identification of Kinematic Variables Specific of Patellar Tendinopathy in Athletes at Risk |
| NCT01460004 | Not specified | COMPLETED | The Effect of Infrapatellar Strap Treatment on Pain Extent and Athletic Measures in Young Athletes |
| NCT01612663 | Not specified | COMPLETED | Effect of Distal Needling on Knee Pain Using Acupuncture Techniques |
| NCT03528746 | Not specified | COMPLETED | The Acute Effect of Isometric Versus Isotonic Resistance Exercise in Patients With Patellar Tendinopathy |
| NCT03694730 | Not specified | COMPLETED | Continued Activity During Rehabilitation in Patients With Patellar Tendinopathy |
| NCT03917849 | Not specified | COMPLETED | Efficacy of Inertial Flywheel vs Heavy Slow Resistance Training Among Athletes With Patellar Tendinopathy |
| NCT04153877 | Not specified | COMPLETED | The Effect of Kinesio-tape® on Pain and Vertical Jump Performance in Active Individuals With Patellar Tendinopathy |
| NCT04219917 | Not specified | COMPLETED | A Comparison of Kinesio® Taping Methods for Subjects With Patellar Tendonitis |
| NCT04339569 | Not specified | COMPLETED | Landing Biomechanics Following Fatigue in Athletes With and Without a History of Patellar Tendinopathy |
| NCT04682496 | Not specified | COMPLETED | Ultrasound Probe Pressure on the Intratendon Doppler Signal in Patellar Tendinopathy |
| NCT04753853 | Not specified | COMPLETED | Stromal Vascular Fraction (SVF) Injection in the Treatment of Patellar Tendinopathy |
| NCT05423366 | Not specified | COMPLETED | Comparative Effects of Focused and Unfocused (Radial) ESWT in the Treatment of Patellar Tendinopathy. |
| NCT05538494 | Not specified | UNKNOWN | Effects on the Patellar Tendon After Low-load Blood Flow Restriction Training. |
| NCT06685302 | Not specified | COMPLETED | Addition of Ultrasound-guided Percutaneous Neuromodulation to Ultrasound-guided Percutaneous Electrolysis and Eccentric Exercises in Patellar Tendinopathy. |
| NCT07356596 | Not specified | COMPLETED | Lower-Extremity Strength and Power in Elite Hockey Players With and Without Patellar Tendinopathy |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.