Pedophilia

Summary

Pedophilia (MONDO:0001692) is a disease and 12 clinical trials. Top therapeutic interventions include leuprolide and cyproterone acetate. A subtype of paraphilic disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 12

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	pedophilia
Mondo ID	MONDO:0001692
MeSH	D010378
DOID	DOID:13351
ICD-10-CM	F65.4
ICD-11	517058174
NCIT	C94355
SNOMED CT	84002002
UMLS	C0030764
MedGen	18340
Is cancer (heuristic)	no

Also known as: Paedophilia

Disease family

This is a subtype of paraphilic disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by developmental or physiological process › psychiatric disorder › sexual disorder › psychosexual disorder › paraphilic disorder › pedophilia

Related subtypes (4): exhibitionism, voyeurism, fetishistic disorder, zoophilia

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 12.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	9
PHASE4	1
PHASE2/PHASE3	1
PHASE3	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01541150	PHASE4	UNKNOWN	Impaired Decision Making in Pedophilic Offenders
NCT00220350	PHASE2/PHASE3	UNKNOWN	Lupron Sex Offender Therapy
NCT00601276	PHASE3	TERMINATED	Comparison of Two Pharmacological Treatments of Pedophilia
NCT06133569	Not specified	RECRUITING	ReDirection - Self Help Program for Individuals with Sexual Interest in Children
NCT06133595	Not specified	RECRUITING	Mi Bridge - Motivational Interviewing to Facilitate Help-seeking Among Individuals with Sexual Interest in Children
NCT06607042	Not specified	NOT_YET_RECRUITING	Study on the Effectiveness of Berlin Dissexuality Therapy as Part of the Model Project in Accordance With §65d SBG V
NCT06778044	Not specified	RECRUITING	ReDirection / Self-Guided ICBT to Reduce the Risk of Child Sexual Abuse Material (CSAM) Use
NCT07001735	Not specified	RECRUITING	Talking for Change: Secondary Prevention of Child Sexual Abuse Perpetration
NCT02822664	Not specified	COMPLETED	Analysis of Cerebral Correlates of Pedophilia With Neuroimaging Techniques
NCT03825627	Not specified	UNKNOWN	From Attention to Behavior: Increasing Behavioral Inhibition
NCT05663047	Not specified	COMPLETED	Prevent It 2.0/GPP -iCBT to Reduce the Risk of Committing Child Sexual Abuse
NCT05831657	Not specified	COMPLETED	Prevent It 2.0/PRIORITY - An iCBT to Reduce the Risk of Committing Child Sexual Abuse

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
LEUPROLIDE	4	5
CYPROTERONE ACETATE	3	1
CHEMBL4303251	0	1
CHEMBL4558169	0	1