Pelvic congestion syndrome
diseaseOn this page
Also known as congestion-fibrosis syndromefemale varicocelePCSpelvic vein incompetenceTaylor syndromeTaylor's syndrome
Summary
Pelvic congestion syndrome (MONDO:0004762) is a disease and 11 clinical trials. Top therapeutic interventions include diosmin. A subtype of uterine disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 11
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | pelvic congestion syndrome |
| Mondo ID | MONDO:0004762 |
| DOID | DOID:9346 |
| SNOMED CT | 39402007 |
| UMLS | C0152078 |
| MedGen | 508874 |
| Is cancer (heuristic) | no |
Also known as: congestion-fibrosis syndrome · female varicocele · PCS · pelvic congestion syndrome · pelvic vein incompetence · Taylor syndrome · Taylor’s syndrome
Disease family
This is a subtype of uterine disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › reproductive system disorder › female reproductive system disorder › uterine disorder › pelvic congestion syndrome
Related subtypes (20): pyometritis, endometrial disorder, female infertility of uterine origin, uterine inflammatory disease, chronic subinvolution of uterus, adhesions of uterus, cervix disorder, uterine polyp, uterine inversion, placenta disorder, hemometra, parametritis, cordiform uterus, septate uterus, bicornuate uterus, uterine hypoplasia, agenesis and aplasia of uterine body, tumor of uterus, florid cystic endosalpingiosis of the uterus, pregnancy, cornual
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 11.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 11 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT06560294 | Not specified | RECRUITING | Glue Embolization vs Conservative Treatment for Pelvic Congestion Syndrome |
| NCT07472504 | Not specified | NOT_YET_RECRUITING | Embolization of Ovarian Vein and Pelvic Venous Reservoir for Treatment of Secondary Pelvic Congestion Syndrome |
| NCT01873287 | Not specified | COMPLETED | Predicting Persistent Postconcussive Problems in Pediatrics (5P) |
| NCT01909024 | Not specified | UNKNOWN | Pelvic Embolisation to Reduce Recurrent Varicose Veins - Recurrent |
| NCT02033863 | Not specified | UNKNOWN | Evaluation of PerformanCe of the Peripheral EOS in the Treatment of Varicocele or Pelvic Congestion SynDromE |
| NCT02796092 | Not specified | COMPLETED | Fibered Platinum Coils vs Vascular Plugs in Pelvic Varices Embolization for the Treatment of Pelvic Congestion Syndrome |
| NCT03921788 | Not specified | COMPLETED | Neuropeptides and Venous Pelvic Pain |
| NCT04115137 | Not specified | UNKNOWN | Pelvic Varicose Veins Treated With Vascular Plugs Type Amplatzer: REPiVAC |
| NCT04512443 | Not specified | COMPLETED | Clinical Efficacy of Conservative Treatment in Female Patients With Plevic Congestion Syndrome |
| NCT05889000 | Not specified | COMPLETED | Quality of Life Questionnaire and Disease Severity Scale |
| NCT06509425 | Not specified | UNKNOWN | Pelvic Congestion Syndrome Post Tubal Ligation Versus Salpingectomy Performed During Caesarean Section |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| DIOSMIN | 4 | 1 |
Related Atlas pages
- Drugs: Diosmin