Pemphigoid gestationis
diseaseOn this page
Also known as gestational pemphigoidHerpes gestationisHerpes gestationis (disorder)Herpes gestationis NOS (disorder)Herpes gestationis unspecified (disorder)
Summary
Pemphigoid gestationis (MONDO:0006558) is a disease. A subtype of pemphigus — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: 1-9 / 1 000 000 (Germany) [Orphanet-validated]
- Phenotypes (HPO): 6
Clinical features
Epidemiology
Prevalence records
4 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Annual incidence | 1-9 / 1 000 000 | 0.2 | Germany | Validated |
| Annual incidence | <1 / 1 000 000 | 0.05 | France | Validated |
| Annual incidence | 1-9 / 1 000 000 | 0.18 | Kuwait | Validated |
| Point prevalence | 1-9 / 1 000 000 | 0.693 | Germany | Validated |
Signs & symptoms
Clinical features (HPO)
6 HPO clinical features (Orphanet curated; top 6 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000989 | Pruritus | Very frequent (80-99%) |
| HP:0001622 | Premature birth | Very frequent (80-99%) |
| HP:0008066 | Abnormal blistering of the skin | Very frequent (80-99%) |
| HP:0200037 | Skin vesicle | Very frequent (80-99%) |
| HP:0001508 | Failure to thrive | Frequent (30-79%) |
| HP:0001511 | Intrauterine growth retardation | Frequent (30-79%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | pemphigoid gestationis |
| Mondo ID | MONDO:0006558 |
| EFO | EFO:1000709 |
| MeSH | D006559 |
| Orphanet | 63275 |
| DOID | DOID:0040098, DOID:14482 |
| ICD-10-CM | O26.4 |
| ICD-11 | 1405755890 |
| NCIT | C85003 |
| SNOMED CT | 86081009 |
| UMLS | C0019343 |
| MedGen | 9233 |
| GARD | 0006497 |
| MedDRA | 10019939 |
| Is cancer (heuristic) | no |
Also known as: gestational pemphigoid · Herpes gestationis · Herpes gestationis (disorder) · Herpes gestationis NOS (disorder) · Herpes gestationis unspecified (disorder) · pemphigoid gestationis
Disease family
This is a subtype of pemphigus. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › integumentary system disorder › skin disorder › dermatitis › autoimmune bullous skin disease › pemphigus › pemphigoid gestationis
Related subtypes (5): Hailey-Hailey disease, pemphigus vulgaris, herpetiform pemphigus, pemphigus erythematosus, pemphigus foliaceus
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.