Peripheral nervous system cancer

Summary

Peripheral nervous system cancer (MONDO:0021089) is a cancer (an umbrella term covering 18 Mondo subtypes). A subtype of peripheral nervous system neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Umbrella term: 18 Mondo subtypes

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	peripheral nervous system cancer
Mondo ID	MONDO:0021089
NCIT	C4961
SNOMED CT	254986007
UMLS	C0751428
MedGen	155556
Anatomy (UBERON)	UBERON:0000010
Is cancer (heuristic)	yes

Also known as: cancer of peripheral nervous system · malignant neoplasm of peripheral nerve · malignant neoplasm of peripheral nervous system · malignant neoplasm of PNS · malignant neoplasm of the peripheral nerve · malignant neoplasm of the peripheral nervous system · malignant neoplasm of the PNS · malignant neoplasms, peripheral nerve · malignant peripheral nerve neoplasm · malignant peripheral nerve tumor · malignant peripheral nerve tumour · malignant peripheral nervous system neoplasm · malignant peripheral nervous system tumor · malignant peripheral nervous system tumour · malignant PNS neoplasm · malignant PNS tumor · malignant PNS tumour · malignant tumor of peripheral nerve · malignant tumor of peripheral nervous system · malignant tumor of PNS (+11 more)

Disease family

This is a subtype of peripheral nervous system neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › peripheral nervous system disorder › peripheral nervous system neoplasm › peripheral nervous system cancer

Related subtypes (8): autonomic nervous system neoplasm, nerve sheath neoplasm, cranial nerve neoplasm, mediastinal neural neoplasm, nerve plexus neoplasm, nerve root neoplasm, peripheral ganglioneuroblastoma, benign neoplasm of peripheral nervous system

Subtypes (18): mediastinum neuroblastoma, malignant cranial nerve neoplasm, granular cell cancer, neurofibroma of gallbladder, adrenal gland ganglioneuroblastoma, malignant carotid body paraganglioma, neurofibroma of the heart, ganglioneuroma, malignant adrenal gland pheochromocytoma, malignant jugulotympanic paraganglioma, pheochromocytoma/paraganglioma syndrome 2, pheochromocytoma/paraganglioma syndrome 5, malignant perineurioma, malignant peripheral nerve sheath tumor, peripheral primitive neuroectodermal tumor, malignant mediastinal neural neoplasm, isolated melanotic schwannoma, cauda equina cancer

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.