Phacoanaphylactic uveitis
disease diseaseOn this page
Also known as endophthalmitis phacoanaphylacticalens-induced endophthalmitislens-induced uveitisPhacoallergic endophthalmitisPhacoantigenic endophthalmitisPhako-anaphylactic endophthalmitis
Summary
Phacoanaphylactic uveitis (MONDO:0016207) is a disease. A subtype of non-infectious anterior uveitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: Unknown (Worldwide)
- Phenotypes (HPO): 30
Clinical features
Signs & symptoms
Clinical features (HPO)
30 HPO clinical features (Orphanet curated; top 30 by frequency):
| HPO ID | Term | Frequency |
|---|---|---|
| HP:0000572 | Visual loss | Very frequent (80-99%) |
| HP:0200026 | Ocular pain | Very frequent (80-99%) |
| HP:0500081 | Pseudophakia | Very frequent (80-99%) |
| HP:0000491 | Keratitis | Frequent (30-79%) |
| HP:0000613 | Photophobia | Frequent (30-79%) |
| HP:0000615 | Abnormal pupil morphology | Frequent (30-79%) |
| HP:0000622 | Blurred vision | Frequent (30-79%) |
| HP:0007773 | Vitreoretinopathy | Frequent (30-79%) |
| HP:0011488 | Abnormal corneal endothelium morphology | Frequent (30-79%) |
| HP:0012122 | Anterior uveitis | Frequent (30-79%) |
| HP:0012123 | Posterior uveitis | Frequent (30-79%) |
| HP:0025337 | Red eye | Frequent (30-79%) |
| HP:0030953 | Conjunctival hyperemia | Frequent (30-79%) |
| HP:0004327 | Abnormal vitreous humor morphology | Occasional (5-29%) |
| HP:0007906 | Ocular hypertension | Occasional (5-29%) |
| HP:0007917 | Tractional retinal detachment | Occasional (5-29%) |
| HP:0008030 | Retinal arteritis | Occasional (5-29%) |
| HP:0011484 | Posterior synechiae of the anterior chamber | Occasional (5-29%) |
| HP:0011505 | Cystoid macular edema | Occasional (5-29%) |
| HP:0011531 | Vitritis | Occasional (5-29%) |
| HP:0011886 | Hyphema | Occasional (5-29%) |
| HP:0012040 | Corneal stromal edema | Occasional (5-29%) |
| HP:0012121 | Panuveitis | Occasional (5-29%) |
| HP:0025341 | Corneal keratic precipitates | Occasional (5-29%) |
| HP:0025561 | Anterior chamber cells grade 1+ | Occasional (5-29%) |
| HP:0030485 | Abnormal amplitude of pattern electroretinogram | Occasional (5-29%) |
| HP:0030486 | Abnormal timing of pattern electroretinogram | Occasional (5-29%) |
| HP:0031615 | Hypopyon | Occasional (5-29%) |
| HP:0031618 | Anterior chamber flare grade 1+ | Occasional (5-29%) |
| HP:0040049 | Macular edema | Occasional (5-29%) |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | phacoanaphylactic uveitis |
| Mondo ID | MONDO:0016207 |
| Orphanet | 209959 |
| SNOMED CT | 410494003 |
| UMLS | C1444621 |
| MedGen | 731803 |
| GARD | 0020443 |
| Is cancer (heuristic) | no |
Also known as: endophthalmitis phacoanaphylactica · lens-induced endophthalmitis · lens-induced uveitis · Phacoallergic endophthalmitis · Phacoantigenic endophthalmitis · Phako-anaphylactic endophthalmitis
Disease family
This is a subtype of non-infectious anterior uveitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › disorder of orbital region › eye disorder › uveal disorder › uveitis › anterior uveitis › non-infectious anterior uveitis › phacoanaphylactic uveitis
Related subtypes (2): Fuchs heterochromic iridocyclitis, sympathetic ophthalmia
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 0.
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.