Pituitary dermoid and epidermoid cysts

disease
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Summary

Pituitary dermoid and epidermoid cysts (MONDO:0019615) is a disease. A subtype of adrenal gland neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Phenotypes (HPO): 24

Clinical features

Signs & symptoms

Clinical features (HPO)

24 HPO clinical features (Orphanet curated; top 24 by frequency):

HPO IDTermFrequency
HP:0000830Anterior hypopituitarismVery frequent (80-99%)
HP:0002017Nausea and vomitingVery frequent (80-99%)
HP:0010885Avascular necrosisVery frequent (80-99%)
HP:0011750Neoplasm of the anterior pituitaryVery frequent (80-99%)
HP:0000135HypogonadismFrequent (30-79%)
HP:0000141AmenorrheaFrequent (30-79%)
HP:0000651DiplopiaFrequent (30-79%)
HP:0000870Increased circulating prolactin concentrationFrequent (30-79%)
HP:0000871PanhypopituitarismFrequent (30-79%)
HP:0000876OligomenorrheaFrequent (30-79%)
HP:0002331Recurrent paroxysmal headacheFrequent (30-79%)
HP:0003324Generalized muscle weaknessFrequent (30-79%)
HP:0007663Reduced visual acuityFrequent (30-79%)
HP:0010514HyperpituitarismFrequent (30-79%)
HP:0012505Enlarged pituitary glandFrequent (30-79%)
HP:0030907Thunderclap headacheFrequent (30-79%)
HP:0100829GalactorrheaFrequent (30-79%)
HP:0000798OligozoospermiaOccasional (5-29%)
HP:0001250SeizureOccasional (5-29%)
HP:0001287MeningitisOccasional (5-29%)
HP:0011442Abnormality of central motor functionOccasional (5-29%)
HP:0011730Abnormality of central sensory functionOccasional (5-29%)
HP:0001117Sudden loss of visual acuityVery rare (<1-4%)
HP:0001959PolydipsiaVery rare (<1-4%)

Identifiers

Disease identifiers

FieldValue
Canonical namepituitary dermoid and epidermoid cysts
Mondo IDMONDO:0019615
Orphanet91351
UMLSC5190781
MedGen1674582
GARD0019161
Is cancer (heuristic)no

Disease family

This is a subtype of adrenal gland neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumorneoplastic disease or syndromeneoplasmendocrine gland neoplasmadrenal gland neoplasmpituitary dermoid and epidermoid cysts

Related subtypes (7): adrenal gland cancer, multiple endocrine neoplasia type 1, Cushing disease due to pituitary adenoma, adrenal medulla neoplasm, benign neoplasm of adrenal gland, pheochromocytoma-paraganglioma, adrenal cortex neoplasm

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.

No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.