Placenta disorder

Summary

Placenta disorder (MONDO:0005917) is a disease (an umbrella term covering 8 Mondo subtypes) and 25 clinical trials. A subtype of uterine disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Umbrella term: 8 Mondo subtypes
• Clinical trials: 25

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	placenta disorder
Mondo ID	MONDO:0005917
EFO	EFO:0007441
MeSH	D010922
DOID	DOID:780
NCIT	C26857
SNOMED CT	125586008
UMLS	C0032045
MedGen	10781
Anatomy (UBERON)	UBERON:0001987
Is cancer (heuristic)	no

Also known as: disease of placenta · disease or disorder of placenta · disease, placenta · disease, placental · diseases, placenta · diseases, placental · disorder of placenta · disorder, placenta · disorders, placenta · placenta disease · placenta disease or disorder · placenta diseases · placenta disorder · placenta disorders · placental disease · placental diseases · placental disorder

Disease family

This is a subtype of uterine disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › reproductive system disorder › female reproductive system disorder › uterine disorder › placenta disorder

Related subtypes (20): pyometritis, endometrial disorder, female infertility of uterine origin, uterine inflammatory disease, chronic subinvolution of uterus, adhesions of uterus, cervix disorder, uterine polyp, pelvic congestion syndrome, uterine inversion, hemometra, parametritis, cordiform uterus, septate uterus, bicornuate uterus, uterine hypoplasia, agenesis and aplasia of uterine body, tumor of uterus, florid cystic endosalpingiosis of the uterus, pregnancy, cornual

Subtypes (8): placental abruption, fetal growth restriction, oligohydramnios, placenta accreta, placenta praevia, placental insufficiency, placenta neoplasm, disorder of extraembryonic membrane

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 25.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	24
PHASE4	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT03674606	PHASE4	COMPLETED	Trial of Early Screening Test for Pre-eclampsia and Growth Restriction
NCT05284474	Not specified	NOT_YET_RECRUITING	Management of Early-onset Fetal Growth Restriction: Angiogenic Factors Versus Feto-placental Doppler
NCT05872009	Not specified	NOT_YET_RECRUITING	Gestational Diabetes Mellitus: Placental-maternal Crosstalk and Future Health
NCT06352970	Not specified	RECRUITING	Effects of Tuberculosis Infection on Development and Function of the Placenta
NCT06992245	Not specified	RECRUITING	Characterization of Placental Diffusion
NCT02577536	Not specified	COMPLETED	PregSource: Crowdsourcing to Understand Pregnancy
NCT02786420	Not specified	COMPLETED	Imaging Innovations for Placental Assessment in Response to Environmental Pollution (PARENTs)
NCT03636698	Not specified	COMPLETED	Effect of Chorioamnionitis on Platelet Activation and Placental Vessel Among Preterm Infants by Wnt-Flt1 Signal Pathway
NCT03731949	Not specified	UNKNOWN	Placental Volume Analysis During Pregnanay
NCT03764878	Not specified	COMPLETED	MARS: Magnetic Resonance Study: A Novel Assessment of Placental Function
NCT04168606	Not specified	COMPLETED	Study on Retroplacental Hematomas in Finistère
NCT04488861	Not specified	UNKNOWN	The START Clinic: a Feasibility Study
NCT04525534	Not specified	TERMINATED	Plasma Concentration of Biological Markers in Placenta Accreta Spectrum
NCT04699578	Not specified	UNKNOWN	COVID-19 Infection and Fetal-neonatal Outcomes
NCT05172674	Not specified	COMPLETED	Ultrasound Diagnosis of Placental and Umbilical Cord Anomalies in Singleton Pregnancies Resulting From In-vitro Fertilization
NCT05245279	Not specified	COMPLETED	Placental Perfusion in the Entire Placenta and With Sonobiopsy by Ultrasound
NCT05644964	Not specified	COMPLETED	The Effect of Anemia in Adolescent and Advanced Age Pregnancies
NCT05720169	Not specified	UNKNOWN	Fetal, Obstetrics and Reproduction Genomics
NCT05739097	Not specified	UNKNOWN	Prospective Study on Feto-maternal outcoMe In aNemIc womEn
NCT05771415	Not specified	COMPLETED	Near-infrared Spectroscopy: Differences in Placental Oxygenation in Relation to Ultrasound Maturation Grade in physiologIcal Term Pregnancies
NCT05899101	Not specified	TERMINATED	The Impact of Opioid and Cannabis Exposure on Fetal Growth
NCT06456645	Not specified	COMPLETED	Effects of Smoking on Placenta and Lactation
NCT06639919	Not specified	COMPLETED	Biochemical and Histological Changes in Pregnant Women With Preterm Premature Rupture of Membrane
NCT06644521	Not specified	COMPLETED	Angiogenic Factors in the Placentas of Women With COVID-19
NCT06668545	Not specified	COMPLETED	Investigating CD 71 in Preeclamptic Pregnancies