Plantar wart
disease diseaseOn this page
Also known as verruca plantaris
Summary
Plantar wart (MONDO:0001795) is a disease and 28 clinical trials. Top therapeutic interventions include acyclovir, bleomycin, and salicylic acid. A subtype of skin disorder caused by infection — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 28
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | plantar wart |
| Mondo ID | MONDO:0001795 |
| EFO | EFO:1002023 |
| DOID | DOID:13775 |
| ICD-10-CM | B07.0 |
| NCIT | C26913 |
| SNOMED CT | 63440008 |
| UMLS | C0042548 |
| MedGen | 53003 |
| Anatomy (UBERON) | UBERON:0008338 |
| Is cancer (heuristic) | no |
Also known as: plantar wart · verruca plantaris
Disease family
This is a subtype of skin disorder caused by infection. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › integumentary system disorder › skin disorder › skin disorder caused by infection › plantar wart
Related subtypes (14): Epstein-Barr virus hepatitis, exanthema subitum, variola major infectious disease, common wart, herpetic whitlow, herpes zoster, chickenpox, hand, foot and mouth disease, viral exanthem, virus-associated trichodysplasia spinulosa, infective dermatitis associated with HTLV-1, skin infection, skin disease caused by bacterial infection, parasitic skin disorder
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 28.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 13 |
| PHASE4 | 5 |
| PHASE2/PHASE3 | 2 |
| PHASE1/PHASE2 | 2 |
| PHASE2 | 2 |
| EARLY_PHASE1 | 2 |
| PHASE3 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT03977753 | PHASE4 | RECRUITING | Randomized, Placebo-controlled, Double Blind Study to Evaluate the Efficacy of 2LVERU®JUNIOR and 2LVERU® on the Treatment of Warts |
| NCT07197541 | PHASE4 | NOT_YET_RECRUITING | A Self-controlled Study of Bleomycin and Pingyangmycin Injection in the Treatment of Plantar Warts |
| NCT07448844 | PHASE4 | RECRUITING | Intralesional Therapies For Cutaneous Viral Warts: A Comparative Analysis Of Vitamin D3 And Acyclovir |
| NCT01059110 | PHASE4 | TERMINATED | Comparison of Five Treatments in Patients With Plantar Warts |
| NCT03183765 | PHASE4 | COMPLETED | Intralesional Measles, Mumps, Rubella (MMR) Vaccine Versus Cryotherapy in Treatment of Multiple Common and Planter Warts |
| NCT02151630 | PHASE2/PHASE3 | UNKNOWN | Pyruvic Acid Versus Salicylic Acid Preparation in Treatment of Plantar Warts |
| NCT05198180 | PHASE3 | UNKNOWN | Treatment of Plantar Warts |
| NCT06261684 | PHASE2/PHASE3 | UNKNOWN | Intralesional Acyclovir Versus Cryotherapy in the Treatment of Plantar Warts. A Randomized Controlled Trial. |
| NCT06718192 | PHASE1/PHASE2 | RECRUITING | A Randomized Controlled Trial to Evaluate the Effectiveness of Bleomycin and Cryotherapy in Treating Plantar Warts. |
| NCT02338336 | PHASE1/PHASE2 | COMPLETED | A Phase I/II Double-blind Safety and Efficacy Evaluation of Nowarta110 in Patients With Plantar Warts |
| NCT02640820 | PHASE2 | UNKNOWN | Evaluate the Effectiveness and Safety of DPCP Ointment (Samcyprone™) on the Clearance of Verruca Vulgaris (Common Warts) |
| NCT05877313 | PHASE2 | COMPLETED | Nitric Oxide Releasing Solution (NORS) For The Treatment Of Human Papillomavirus(HPV) Verrucae Plantaris (Plantar Warts) |
| NCT05588999 | PHASE1 | COMPLETED | Comparative Study Between Treatment With Cryotherapy Alone Versus Cryotherapy Plus Salicylic Acid Dressing for Planter Warts |
| NCT04823845 | EARLY_PHASE1 | WITHDRAWN | Plantar Wart Treatment Using Adapalene Gel |
| NCT05592041 | EARLY_PHASE1 | COMPLETED | Studying of Natural Constituents’ Treatment of Plantar Warts |
| NCT00328991 | Not specified | COMPLETED | Clinical Trial Evaluating Efficacy of Duct Tape for Treatment of Warts |
| NCT01330615 | Not specified | UNKNOWN | Efficacy Trial of Eutectic Lidocaine/Prilocaine Cream 5% (EMLA) for Analgesia Prior to Cryotherapy of Verrucae Plantaris |
| NCT01536834 | Not specified | COMPLETED | Safety & Performance Study of Verruca Treatment Device |
| NCT02861404 | Not specified | TERMINATED | Evaluation of Viral Status of Patients With Plantar Warts Included in VRAIE Study, Non-responder to Study Treatment |
| NCT04654091 | Not specified | UNKNOWN | Cryotherapy VS. Nitric-zinc Complex in the Treatment of Plantar Warts. |
| NCT05057663 | Not specified | UNKNOWN | Intralesional Treatment of Plantar Wart |
| NCT05115669 | Not specified | COMPLETED | Safety & Effectiveness of Wortie Freeze Plus in Common and Plantar Warts |
| NCT05324904 | Not specified | UNKNOWN | Intralesional Vitamin D3 Versus Intralesional Acyclovir in Treatment of Plantar Warts |
| NCT05488860 | Not specified | UNKNOWN | Piezoelectric Drived Microneedling in Treating Refractory Skin Diseases |
| NCT05520658 | Not specified | UNKNOWN | Evaluation of the Efficacy of Intralesional Injection of Combined Digoxin and Furosemide Versus 5 - Fluorouracil in Treatment of Plantar Warts |
| NCT05599971 | Not specified | UNKNOWN | Intralesional Injection of Combined Digoxin and Furosemide Versus 5-Flurouracil in Plantar Warts |
| NCT06214559 | Not specified | COMPLETED | Evaluate the Effectiveness and the Safety of a Medical Device in the Treatment of Common Warts and Plantar Warts. |
| NCT06958237 | Not specified | COMPLETED | Salicylic Acid Wart Patch for the Treatment of Common Warts and Plantar Warts |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| ACYCLOVIR | 4 | 3 |
| BLEOMYCIN | 4 | 3 |
| SALICYLIC ACID | 4 | 2 |
| FLUOROURACIL | 4 | 1 |
| IMIQUIMOD | 4 | 1 |
| LIDOCAINE HYDROCHLORIDE | 4 | 1 |
| NITRIC OXIDE | 4 | 1 |
| PYRUVATE | 2 | 1 |
| SODIUM SALICYLATE | 1 | 1 |
Related Atlas pages
- Drugs: Acyclovir, Bleomycin, Salicylic Acid, Fluorouracil, Imiquimod, Lidocaine, Nitric Oxide