Pleomorphic adenoma

Summary

Pleomorphic adenoma (MONDO:0008401) is a cancer. A subtype of benign digestive system neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	pleomorphic adenoma
Mondo ID	MONDO:0008401
MeSH	D008949
OMIM	181030
Orphanet	454821
DOID	DOID:452
NCIT	C8602
SNOMED CT	447888006
UMLS	C1519176
MedGen	275400
GARD	0017789
Is cancer (heuristic)	yes

Also known as: adenomas, salivary gland pleomorphic, somatic · mixed tumour of the salivary gland · pleomorphic adenoma · pleomorphic adenoma (morphologic abnormality) · tumor, mixed, benign

Disease family

This is a subtype of benign digestive system neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › benign digestive system neoplasm › pleomorphic adenoma

Related subtypes (9): intestinal benign neoplasm, bile duct papillary neoplasm, hepatocellular adenoma, benign neoplasm of stomach, benign neoplasm of esophagus, benign neoplasm of pancreas, benign neoplasm of oropharynx, benign neoplasm of gallbladder, hepatobiliary benign neoplasm

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.