Pleural solitary fibrous tumor

Summary

Pleural solitary fibrous tumor (MONDO:0021041) is a cancer and 3 clinical trials. A subtype of solitary fibrous tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	pleural solitary fibrous tumor
Mondo ID	MONDO:0021041
NCIT	C4457
SNOMED CT	254646001
GARD	0025278
Anatomy (UBERON)	UBERON:0000977
Is cancer (heuristic)	yes

Also known as: fibroma of pleura · fibroma of the pleura · localised fibrous mesothelioma of pleura · localised fibrous mesothelioma of the pleura · localized fibrous mesothelioma of pleura · localized fibrous mesothelioma of the pleura · pleura solitary fibrous tumor · pleura solitary fibrous tumour · pleural cavity solitary fibrous tumor · pleural cavity solitary fibrous tumour · pleural fibroma · pleural solitary fibrous tumor · pleural Submesothelial fibroma · solitary fibrous tumor of pleura · solitary fibrous tumor of the pleura · solitary fibrous tumour of pleura · solitary fibrous tumour of the pleura

Data availability: 3 cell lines.

Disease family

This is a subtype of solitary fibrous tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › mesenchymal cell neoplasm › fibroblastic neoplasm › solitary fibrous tumor › pleural solitary fibrous tumor

Related subtypes (4): liver solitary fibrous tumor, dedifferentiated solitary fibrous tumor, hemangiopericytoma, malignant, peritoneal solitary fibrous tumor

Subtypes (1): malignant pleural solitary fibrous tumor

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02613299	Not specified	TERMINATED	Surgery for Mesothelioma After Radiation Therapy SMART for Resectable Malignant Pleural Mesothelioma
NCT02613312	Not specified	TERMINATED	Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma
NCT02648763	Not specified	TERMINATED	Staging Procedures to Diagnose Malignant Pleural Mesothelioma