Polyarticular juvenile rheumatoid arthritis

Summary

Polyarticular juvenile rheumatoid arthritis (MONDO:0023249) is a disease and 2 clinical trials. A subtype of rheumatoid arthritis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	polyarticular juvenile rheumatoid arthritis
Mondo ID	MONDO:0023249
SNOMED CT	445479007
UMLS	C0311221
MedGen	551885
GARD	0010967
Is cancer (heuristic)	no

Also known as: Juvenile polyarthritis rheumatoid factor negative · Juvenile polyarthritis rheumatoid factor positive

Disease family

This is a subtype of rheumatoid arthritis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › autoimmune disorder of musculoskeletal system › rheumatoid arthritis › polyarticular juvenile rheumatoid arthritis

Related subtypes (6): rheumatoid arthritis-associated interstitial lung disease, chronic childhood arthritis, ankylosing spondylitis, Felty syndrome, psoriatic arthritis, rheumatoid vasculitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	2

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01304420	Not specified	COMPLETED	Ultrasonography in Juvenile Idiopathic Arthritis
NCT02593006	Not specified	COMPLETED	Start Time Optimization of Biologics in Polyarticular JIA