Polyp of rectum

Summary

Polyp of rectum (MONDO:0021398) is a disease and 13 clinical trials. A subtype of rectal disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 13

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	polyp of rectum
Mondo ID	MONDO:0021398
ICD-10-CM	K62.1
ICD-11	2101432719
NCIT	C3351
SNOMED CT	39772007
UMLS	C0034887
MedGen	11150
Anatomy (UBERON)	UBERON:0001052
Is cancer (heuristic)	no

Also known as: polyp of the rectum · rectal polyp · rectum polyp

Disease family

This is a subtype of rectal disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › large intestine disorder › rectal disorder › polyp of rectum

Related subtypes (5): anal fistula, ulcer of anus and rectum, rectal neoplasm, anus disorder, rectal prolapse

Subtypes (2): rectal hyperplastic polyp, anal polyp

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 13.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	11
PHASE3	1
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00467922	PHASE3	COMPLETED	An Assessment of Goal-Directed Intraoperative Fluid Management in Hand Assisted Laparoscopic Colectomy
NCT05776381	PHASE2	NOT_YET_RECRUITING	The Impact of a Patient Decision Aid on Treatment Choices for Patients With an Unexpected Malignant Colorectal Polyp
NCT05551052	Not specified	ACTIVE_NOT_RECRUITING	CRC Detection Reliable Assessment With Blood
NCT05793554	Not specified	RECRUITING	CLASSICA: Validating AI in Classifying Cancer in Real-Time Surgery
NCT06133387	Not specified	RECRUITING	PARADIGM - En Bloc Trial With the EndoQuest Endoluminal Surgical (ELS) System
NCT06286956	Not specified	ACTIVE_NOT_RECRUITING	Rectal Tumor Resection Using the UNI-VEC Multichannel Transanal Access Device
NCT07341126	Not specified	NOT_YET_RECRUITING	Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal
NCT01712048	Not specified	COMPLETED	Submucosal Injection EMR vs. Underwater EMR for Colorectal Polyps
NCT02579330	Not specified	UNKNOWN	Trial on Use of Coloshield in Transanal and Anal Surgery
NCT03700593	Not specified	UNKNOWN	Feasibility and Safety of Single Port Robot in Colorectal Procedures
NCT04651764	Not specified	TERMINATED	Transanal Resection of Rectal Lesions With the ColubrisMX ELS System
NCT04889352	Not specified	COMPLETED	Optimizing Timing of Follow-up Colonoscopy
NCT04977401	Not specified	TERMINATED	EndoscoPic Submucosal dIssection Using geL Versus glycerOl for Submucosal iNjection

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
CHEMBL443232	0	1