Postprandial hypotension

Summary

Postprandial hypotension (MONDO:0005470) is a disease and 7 clinical trials. Top therapeutic interventions include acarbose. A subtype of hypotensive disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 7

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	postprandial hypotension
Mondo ID	MONDO:0005470
Is cancer (heuristic)	no

Disease family

This is a subtype of hypotensive disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › vascular disorder › arterial disorder › hypotensive disorder › postprandial hypotension

Related subtypes (4): supine hypotensive syndrome, acute hypotension, orthostatic hypotension, neurally mediated hypotension

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 7.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	6
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02043886	PHASE2	COMPLETED	Acarbose, Postprandial Hypotension and Type 2 Diabetes
NCT05575661	Not specified	RECRUITING	Correlation Between Postprandial Hypotension and Post-induction Hypotension in the Elderly.
NCT06208904	Not specified	ENROLLING_BY_INVITATION	The Involvement of the Gut Hormone GIP in the Pathophysiology of Post Prandial Hypotension
NCT07381816	Not specified	ENROLLING_BY_INVITATION	GastroFlow: Investigation of the Gastrointestinal Blood Flow in Patients With Postprandial Hypotension
NCT07485998	Not specified	NOT_YET_RECRUITING	Orthostatic And Postprandial Hypotension In Hospitalized Older Adults (HOPE65)
NCT05334342	Not specified	COMPLETED	Low-GI Diet Vs High-GI Diet in Individuals with SCI
NCT06657287	Not specified	COMPLETED	Postprandial Hypotension and Insulin Levels

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
ACARBOSE	4	1
CHEMBL4299399	0	1
CHEMBL4760828	0	1