Postsurgical hypothyroidism

Summary

Postsurgical hypothyroidism (MONDO:0002002) is a disease and 2 clinical trials. Top therapeutic interventions include levothyroxine. A subtype of hypothyroidism — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 2

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	postsurgical hypothyroidism
Mondo ID	MONDO:0002002
DOID	DOID:1458
SNOMED CT	27059002
UMLS	C0154157
MedGen	509534
Is cancer (heuristic)	no

Disease family

This is a subtype of hypothyroidism. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › endocrine system disorder › thyroid gland disorder › hypothyroidism › postsurgical hypothyroidism

Related subtypes (5): iodine hypothyroidism, myxedema, congenital hypothyroidism, myxedema coma, myxedema heart disease

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 2.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE4	1
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02946918	PHASE4	TERMINATED	Levothyroxine Replacement With Liquid Gel Capsules vs Tablets Post-thyroidectomy
NCT02567877	Not specified	TERMINATED	Is Levothyroxine Alone Adequate Thyroid Hormone Replacement?

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
LEVOTHYROXINE	4	1