Prolactin producing pituitary tumor

disease

On this page

Also known as malignant prolactin producing neoplasm of pituitary glandmalignant prolactinomaPRL producing pituitary gland neoplasmprolactin producing neoplasm of pituitaryprolactin producing neoplasm of pituitary glandprolactin producing neoplasm of the pituitaryprolactin producing neoplasm of the pituitary glandprolactin producing pituitary gland neoplasmprolactin producing pituitary gland tumorprolactin producing pituitary gland tumourprolactin producing pituitary neoplasmprolactin producing tumor of pituitaryprolactin producing tumor of pituitary glandprolactin producing tumor of the pituitaryprolactin producing tumor of the pituitary glandprolactin producing tumour of pituitaryprolactin producing tumour of pituitary glandprolactin producing tumour of the pituitaryprolactin producing tumour of the pituitary glandprolactin secreting neoplasm of pituitary

Summary

Prolactin producing pituitary tumor (MONDO:0003430) is a cancer and 3 clinical trials. Top therapeutic interventions include dopamine and pasireotide. A subtype of pituitary tumor — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

Classification: Cancer
Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	prolactin producing pituitary tumor
Mondo ID	MONDO:0003430
DOID	DOID:5396
NCIT	C7910
UMLS	C0278863
MedGen	82998
GARD	0023508
Is cancer (heuristic)	yes

Also known as: malignant prolactin producing neoplasm of pituitary gland · malignant prolactinoma · PRL producing pituitary gland neoplasm · prolactin producing neoplasm of pituitary · prolactin producing neoplasm of pituitary gland · prolactin producing neoplasm of the pituitary · prolactin producing neoplasm of the pituitary gland · prolactin producing pituitary gland neoplasm · prolactin producing pituitary gland tumor · prolactin producing pituitary gland tumour · prolactin producing pituitary neoplasm · prolactin producing tumor of pituitary · prolactin producing tumor of pituitary gland · prolactin producing tumor of the pituitary · prolactin producing tumor of the pituitary gland · prolactin producing tumour of pituitary · prolactin producing tumour of pituitary gland · prolactin producing tumour of the pituitary · prolactin producing tumour of the pituitary gland · prolactin secreting neoplasm of pituitary (+18 more)

Disease family

This is a subtype of pituitary tumor. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › endocrine gland neoplasm › pituitary tumor › prolactin producing pituitary tumor

Subtypes (2): prolactin-producing pituitary gland carcinoma, prolactin-producing pituitary gland adenoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
PHASE4	1
PHASE2	1
Not specified	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04107480	PHASE4	UNKNOWN	PRolaCT - Three Prolactinoma RCTs
NCT06295952	PHASE2	RECRUITING	A Study of Pasireotide in People With Prolactinoma
NCT04106531	Not specified	TERMINATED	Validation of a Quality of Life Metric Prolac-10

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
DOPAMINE	4	3
PASIREOTIDE	4	1

Drugs: Dopamine, Pasireotide