Puerperal infection

Summary

Puerperal infection (MONDO:0021742) is a disease and 5 clinical trials. Top therapeutic interventions include chlorhexidine and povidone-iodine. A subtype of infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 5

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	puerperal infection
Mondo ID	MONDO:0021742
EFO	EFO:1001407
MeSH	D011645
UMLS	C0034041
MedGen	11022
Is cancer (heuristic)	no

Also known as: Infection, Puerperal · Infections, Puerperal · Puerperal Infections

Disease family

This is a subtype of infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › puerperal infection

Related subtypes (34): infective endocarditis, hirudiniasis, fungal infectious disease, infectious peritonitis, epididymitis, viral infectious disease, bacterial infectious disease, parasitic infectious disease, abscess, Ciliophora infectious disease, hookworm infectious disease, infectious embryofetopathy, mycetoma, infectious disorder of the nervous system, ear infection, sexually transmitted disease, Acanthamoeba infectious disease, infectious myositis, infective vaginitis, skin disorder caused by infection, respiratory tract infectious disorder, nail infection, infective arthritis, digestive system infectious disorder, nosocomial infection, eye infectious disorder, prosthesis-related infectious disease, vector-borne disease, coinfection, urinary tract infection, hemorrhagic fever, protothecosis, pythiosis, infectious disease with sepsis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 5.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3
PHASE3	1
PHASE2/PHASE3	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00136370	PHASE3	UNKNOWN	Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
NCT01039051	PHASE2/PHASE3	UNKNOWN	Diet and Lifestyle Intervention Study in Postpartum Women in China
NCT03397615	Not specified	UNKNOWN	Effect of Vaginal Douching With Betadine Before CS for Prevention of Post Operative Infections
NCT04763486	Not specified	UNKNOWN	Prophylactic Antibiotic After Perineal Tear
NCT05603624	Not specified	TERMINATED	Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
CHLORHEXIDINE	4	1
POVIDONE-IODINE	4	1