Pulmonary valve disorder

Summary

Pulmonary valve disorder (MONDO:0003628) is a disease and 4 clinical trials. A subtype of heart valve disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	pulmonary valve disorder
Mondo ID	MONDO:0003628
EFO	EFO:0009564
DOID	DOID:5749
ICD-11	1146446025
NCIT	C78579
SNOMED CT	76267008
UMLS	C0034087
MedGen	18767
Anatomy (UBERON)	UBERON:0002146
Is cancer (heuristic)	no

Also known as: disease of pulmonary valve · disease or disorder of pulmonary valve · disorder of pulmonary valve · pulmonary valve disease · pulmonary valve disease or disorder · pulmonary valve disorder

Disease family

This is a subtype of heart valve disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › cardiovascular disorder › heart disorder › heart valve disorder › pulmonary valve disorder

Related subtypes (3): tricuspid valve disorder, mitral valve disorder, aortic valve disorder

Subtypes (3): pulmonary valve insufficiency, rheumatic pulmonary valve disease, pulmonary valve stenosis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	4

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05979870	Not specified	ENROLLING_BY_INVITATION	Artificial Intelligence in New Cardiac MR Markers for Congenital Heart Disease
NCT07267117	Not specified	RECRUITING	Cohort Observing Mechanisms, Progression and Sequelae of Valvular Heart Disease
NCT04152967	Not specified	UNKNOWN	New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract
NCT05583656	Not specified	UNKNOWN	INSPIRIS RESILIA Valve in Pulmonary Position