Radiation cystitis

Summary

Radiation cystitis (MONDO:0004112) is a disease and 7 clinical trials. A subtype of cystitis — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 7

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	radiation cystitis
Mondo ID	MONDO:0004112
DOID	DOID:7127
ICD-10-CM	N30.4
NCIT	C123174
SNOMED CT	11251000
UMLS	C0156270
MedGen	510221
Is cancer (heuristic)	no

Also known as: irradiation cystitis

Disease family

This is a subtype of cystitis. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › urinary system disorder › urinary bladder disorder › cystitis › radiation cystitis

Related subtypes (13): hemorrhagic cystitis, prostatocystitis, acute cystitis, diphtheritic cystitis, trigonitis, cystitis cystica, emphysematous cholecystitis, chronic cystitis, acalculous cholecystitis, gonococcal cystitis, pyelocystitis, eosinophilic cryptitis, Trichomonas cystitis

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 7.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	5
PHASE2/PHASE3	1
EARLY_PHASE1	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05245591	PHASE2/PHASE3	RECRUITING	Radiation Cystitis Treated With Pentosan Polysulfate Sodium Trial
NCT07016451	EARLY_PHASE1	COMPLETED	Efficacy of Low-Intensity Shockwave Therapy in Treating Radiation Cystitis
NCT04701749	Not specified	RECRUITING	Study of the Effects of Anticoagulant Interruption Covered by Percutaneous Left Atrial Occlusion in Patients With Chronic Atrial Fibrillation and Radiation Cystitis at Risk of Bleeding
NCT07125924	Not specified	NOT_YET_RECRUITING	Intravesical Hyaluronic Acid (HA) for Preventing Radiation Cystitis on Bladder Cancer
NCT07259681	Not specified	NOT_YET_RECRUITING	Gut Microbiome in Gynecological Cancer Patients With Pelvic Toxicity: Controls Versus Ozone Treatment. (MicrOzoGineTox)
NCT07368647	Not specified	RECRUITING	Chronic Radiation Cystitis and Effect of Hyperbaric Oxygen Therapy on Patient Reported Outcomes and Urine Inflammatory Biomarkers
NCT05246774	Not specified	UNKNOWN	Study of Serum and Urinary Biomarkers and Radiation Cystitis in Patients Treated With Radiotherapy for Localized Prostate Cancer