Radius fracture
disease diseaseOn this page
Summary
Radius fracture (MONDO:0005325) is a disease and 37 clinical trials. Top therapeutic interventions include dibotermin alfa, ropivacaine, and rusalatide acetate. A subtype of bone fracture — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Clinical trials: 37
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | radius fracture |
| Mondo ID | MONDO:0005325 |
| EFO | EFO:0003957 |
| MeSH | D011885 |
| SNOMED CT | 12676007 |
| Is cancer (heuristic) | no |
Disease family
This is a subtype of bone fracture. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: injury › bone fracture › radius fracture
Related subtypes (6): spinal fracture, humerus fracture, tibia fracture, ulna fracture, hip fracture, jaw fracture
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
Drugs indicated or in trials for this disease
No drug has an approved disease-direct ChEMBL indication for this disease.
2 drugs in clinical trials for this disease (phase 2–3, investigational): efficacy not established — a trial record, not an indication.
| Drug | Highest phase |
|---|---|
| Bupivacaine | Phase 3 |
| Teriparatide | Phase 2 |
Clinical trials & evidence
Clinical trials
Clinical trials: 37.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 32 |
| PHASE4 | 2 |
| PHASE3 | 1 |
| PHASE2 | 1 |
| PHASE1 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT00274378 | PHASE4 | COMPLETED | Allomatrix Injectable Putty in Distal Radius Fractures |
| NCT02630290 | PHASE4 | COMPLETED | Addition of Dexmedetomidine to Ropivacaine-induced Supraclavicular Block (ADRIB Trial) |
| NCT00908895 | PHASE3 | COMPLETED | Non-bridging Fixator Versus Percutaneous Pinning for Distal Radius Fractures |
| NCT00131482 | PHASE2 | TERMINATED | A Study to Evaluate the Safety and Effectiveness of Different Doses of Chrysalin in Adults Who Have a Broken Wrist |
| NCT00161629 | PHASE1 | COMPLETED | Study Evaluating rhBMP-2/CPM in Closed Distal Radius Fractures |
| NCT06998914 | Not specified | NOT_YET_RECRUITING | Arthroscopic Assisted Distal Radius Fracture Fixation |
| NCT07037355 | Not specified | ACTIVE_NOT_RECRUITING | Association Between Hand-Eye Coordination and Handgrip Strength in Children Post-Healing of DRGF |
| NCT07263295 | Not specified | NOT_YET_RECRUITING | Evaluation of Diaphragmatic Function After Interscalene Block With Liposomal Bupivacaine |
| NCT07429344 | Not specified | RECRUITING | EASY Algorithm Trial (Elbow Trauma Assessment Using Sonography in Children and Youth) Diagnostic Accuracy and Safety of Point-of-care Ultrasound as a Screening Tool for Suspected Elbow Fractures in Children Aged 5 to 15 Years: a Multicenter Prospective Cohort Study |
| NCT07536581 | Not specified | NOT_YET_RECRUITING | Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails |
| NCT00271726 | Not specified | UNKNOWN | Operative Treatment of Extraarticular Colles’ Fractures of the Distal Radius (OTEC) |
| NCT00587795 | Not specified | TERMINATED | Orthopedic Study of the Aircast StabilAir Wrist Fracture Brace |
| NCT00816998 | Not specified | COMPLETED | Range of Motion and Patients With Distal Radius Fractures |
| NCT00955734 | Not specified | COMPLETED | Early Motion After Volar Fixation for Distal Radius Fractures |
| NCT00989222 | Not specified | COMPLETED | Volar Plating or External Fixation of Dorsally Displaced Fractures of the Distal Radius? |
| NCT01262807 | Not specified | COMPLETED | Reducing Range of Motion Deficits Post Radial Fracture |
| NCT01493167 | Not specified | COMPLETED | Study on Wood-plastic Composite for Circumferential Casting |
| NCT02348437 | Not specified | COMPLETED | Repair vs Non-repair of the Pronator Quadratus Muscle in Distal Radius Fractures. RCT. |
| NCT02353338 | Not specified | COMPLETED | Distal Radial Fractures in the Late Middle Aged |
| NCT02505633 | Not specified | COMPLETED | Comparison 1 Plane-1 Injection and 2 Plane-2 Injection Ultrasound-guided Supraclavicular Brachial Plexus Block |
| NCT02514343 | Not specified | COMPLETED | Magnesium Sulfate and Bupivacaine for Rehabilitation After Distal Radius Fractures |
| NCT02522403 | Not specified | COMPLETED | Acupuncture in Distal Radius Fracture Patients |
| NCT02533557 | Not specified | COMPLETED | Comparison 1 Plane-2 Injection and 2 Plane-2 Injection Ultrasound-guided Supraclavicular Brachial Plexus Block |
| NCT02670629 | Not specified | COMPLETED | Management of Distal Radius Fractures in Children Younger Than 11 Years Old. |
| NCT02782299 | Not specified | TERMINATED | Shared Decision Making in Older Adults With Distal Radius Fractures |
| NCT02840188 | Not specified | COMPLETED | Young Goalkeeper’s Fracture: Radiographic Findings |
| NCT03297047 | Not specified | COMPLETED | Comparing Forearm and Upper Arm Combi Cast for Distal Forearm Fractures in Children |
| NCT03423043 | Not specified | COMPLETED | Low Dose CT Distal Radius Fractures |
| NCT03438864 | Not specified | COMPLETED | Acute Effects of Interferential Current on Edema, Pain and Muscle Strength in Patients With Distal Radius Fracture |
| NCT03496337 | Not specified | COMPLETED | Is AMPS a Responsive Tool for Assessing Change in ADL-abilities After Finger or Hand Surgery |
| NCT03531801 | Not specified | COMPLETED | Referred Pain Areas in Subjects With a Recovered Radius Fracture |
| NCT03570905 | Not specified | COMPLETED | Radiographic and Clinical Comparison of Post-reduction Splinting Constructs in the Treatment of Acute Displaced Distal Radius Fractures |
| NCT04062110 | Not specified | COMPLETED | Below-elbow or Above-elbow Cast for Extra-articular Distal Radius Fractures |
| NCT04930718 | Not specified | UNKNOWN | Thumb and Wrist Proprioception Exercises. |
| NCT06067074 | Not specified | UNKNOWN | Cost-effectiveness, Volar Locking Plate or Non-operative Treatment Distal Radius Fracture |
| NCT06588907 | Not specified | COMPLETED | Pain Palliation in Forearm Fractures in the Emergency Department |
| NCT06738693 | Not specified | COMPLETED | External Fixation Vs. Volar Plate for Distal Radius Fractures: Functional Outcomes |
Drugs tested across these trials (top 30)
| Molecule | Max phase | Trials referencing |
|---|---|---|
| DIBOTERMIN ALFA | 4 | 1 |
| ROPIVACAINE | 4 | 1 |
| RUSALATIDE ACETATE | 2 | 1 |
Related Atlas pages
- Drugs: Dibotermin Alfa, Ropivacaine