Rectum adenoma

disease

On this page

Also known as adenoma of rectumadenoma of the rectumrectal adenoma

Summary

Rectum adenoma (MONDO:0000530) is a cancer and 7 clinical trials. A subtype of colorectal adenoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

Classification: Cancer
Clinical trials: 7

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	rectum adenoma
Mondo ID	MONDO:0000530
DOID	DOID:0050915
NCIT	C5546
SNOMED CT	399730005
UMLS	C1302652
MedGen	266267
Anatomy (UBERON)	UBERON:0001052
Is cancer (heuristic)	yes

Also known as: adenoma of rectum · adenoma of the rectum · rectal adenoma · rectum adenoma

Disease family

This is a subtype of colorectal adenoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › intestinal neoplasm › colorectal neoplasm › colorectal adenoma › rectum adenoma

Subtypes (4): rectal traditional serrated adenoma, rectal tubular adenoma, rectal tubulovillous adenoma, rectal villous adenoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 7.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	7

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06133387	Not specified	RECRUITING	PARADIGM - En Bloc Trial With the EndoQuest Endoluminal Surgical (ELS) System
NCT07341126	Not specified	NOT_YET_RECRUITING	Use of a Novel Camera to Check the Bowel After Polyp or Tumour Removal
NCT07410767	Not specified	NOT_YET_RECRUITING	Advanced Endoscopic Resections for Rectal Neoplasms
NCT01498354	Not specified	COMPLETED	Efficiency of Two Dimensional High Definition vs Three Dimensional Endoscopic Systems in Transanal Endoscopic Surgery
NCT02579330	Not specified	UNKNOWN	Trial on Use of Coloshield in Transanal and Anal Surgery
NCT04651764	Not specified	TERMINATED	Transanal Resection of Rectal Lesions With the ColubrisMX ELS System
NCT06158776	Not specified	COMPLETED	Predicting Rectal Adenoma With Canceration and Investigating Mechanism Based on Multimodal MRI and Biochemical Model

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
CHEMBL443232	0	1

No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.