Refeeding syndrome

Summary

Refeeding syndrome (MONDO:0400005) is a disease and 13 clinical trials. A subtype of nutritional disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 13

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	refeeding syndrome
Mondo ID	MONDO:0400005
MeSH	D055677
UMLS	C0860549
MedGen	167819
Is cancer (heuristic)	no

Disease family

This is a subtype of nutritional disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › nutritional disorder › refeeding syndrome

Related subtypes (6): potassium deficiency disease, overnutrition, eating disorder, hemorrhagic disease of newborn, nutritional deficiency disease, lactose intolerance

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 13.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	11
PHASE4	1
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT02880072	PHASE4	COMPLETED	Absorption of Orally Ingested Phosphate in Refeeding Syndrome
NCT02534181	PHASE2	WITHDRAWN	Refeeding Syndrome in Cancer Patients
NCT06583928	Not specified	NOT_YET_RECRUITING	Refeeding Syndrome in Critically Ill Children
NCT06589479	Not specified	NOT_YET_RECRUITING	Prevention of Refeeding Syndrome
NCT06825377	Not specified	RECRUITING	Comparing High-protein Vs. Standard Protein Nutritional Support in Critically Ill Patients At Risk for Refeeding Syndrome
NCT01227850	Not specified	COMPLETED	Leptin, IGF1 and the Refeeding Index
NCT01845922	Not specified	COMPLETED	The Effect of a Diet Based on Low Sodium and Slowly Absorbed Carbohydrates on the Incidence of Refeeding Syndrome in Patients With Head and Neck Cancer
NCT03141489	Not specified	COMPLETED	Refeeding Syndrome Among Older Adults
NCT03537170	Not specified	COMPLETED	Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, India
NCT04966780	Not specified	COMPLETED	Refeeding Like Syndrome in Acute Disease
NCT05967858	Not specified	COMPLETED	Incidence of Refeeding Syndrome in Consecutively Admitted Patients
NCT06054139	Not specified	UNKNOWN	Risk Factors for Refeeding Syndrome in the Surgical Intensive Care Unit
NCT06344546	Not specified	COMPLETED	Metabolic Pathway Analysis in Intensive Care Unit Patients With Refeeding Syndrome