Sacrococcygeal teratoma

Summary

Sacrococcygeal teratoma (MONDO:0042727) is a disease and 4 clinical trials. A subtype of vertebral column disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	sacrococcygeal teratoma
Mondo ID	MONDO:0042727
Orphanet	494421
NCIT	C99055
SNOMED CT	281561000
UMLS	C0559459
MedGen	107852
GARD	0000319
NORD	1685
Anatomy (UBERON)	UBERON:0001350
Is cancer (heuristic)	no

Also known as: pre-sacral teratoma · presacral teratoma · sacrococcygeal teratoma

Data availability: 1 HPO phenotype · 4 cell lines.

Disease family

This is a subtype of vertebral column disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › musculoskeletal system disorder › skeletal system disorder › vertebral column disorder › sacrococcygeal teratoma

Related subtypes (14): spondylocostal dysostosis, sacrum chordoma, epidural spinal canal neoplasm, Baastrup syndrome, lumbosacral lipoma, spinal stenosis, intervertebral disk degenerative disorder, coccygodynia, vertebral joint disorder, spinal cord injury, tuberculosis, spinal, vertebral disorder, lumbar disk disease, dropped head syndrome

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	4

Top trials by phase / activity

NCT	Phase	Status	Title
NCT00780117	Not specified	COMPLETED	Characterization of At-risk Population for Pre-sacral Tumor in CURRARINO Syndrome
NCT04623658	Not specified	COMPLETED	Improving Prenatal Parental Counseling in Cases of Sacrococcygeal Teratoma
NCT05182853	Not specified	COMPLETED	Voiding Disorders in Children After Sacrococcygeal Teratoma Resection
NCT06133036	Not specified	UNKNOWN	Fecal Continence Outcomes and Quality of Life After Excision of Sacrococcygeal Teratoma (Retrospective Study)