Salmonellosis
disease diseaseOn this page
Also known as infections, Salmonellarare form of salmonellosisSalmonella infection
Summary
Salmonellosis (MONDO:0000827) is a disease (an umbrella term covering 5 Mondo subtypes) and 10 clinical trials. Top therapeutic interventions include sodium chloride, ampicillin sodium, and ceftriaxone sodium. A subtype of primary bacterial infectious disease — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Prevalence: 1-9 / 100 000 (Europe)
- Umbrella term: 5 Mondo subtypes
- Clinical trials: 10
Clinical features
Epidemiology
Prevalence records
1 prevalence record(s), Orphanet:
| Type | Class | Value | Geography | Validation |
|---|---|---|---|---|
| Point prevalence | 1-9 / 100 000 | Europe | Not yet validated |
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | salmonellosis |
| Mondo ID | MONDO:0000827 |
| MeSH | D012480 |
| Orphanet | 795 |
| DOID | DOID:0060859 |
| NCIT | C157974 |
| SNOMED CT | 302231008 |
| UMLS | C0036117 |
| MedGen | 48542 |
| MedDRA | 10039447 |
| Is cancer (heuristic) | no |
Also known as: infections, Salmonella · rare form of salmonellosis · Salmonella infection
Disease family
This is a subtype of primary bacterial infectious disease. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by etiologic mechanism › disease of primarily extrinsic mechanism › infectious disease › bacterial infectious disease › primary bacterial infectious disease › salmonellosis
Related subtypes (36): Buruli ulcer disease, sennetsu fever, pinta disease, chancroid, gonorrhea, anthrax infection, leprosy, botulism, diphtheria, tetanus, bartonellosis, brucellosis, campylobacteriosis, glanders, granuloma inguinale, legionellosis, leptospirosis, listeriosis, Mycobacterium avium complex disease, ornithosis, rhinoscleroma, staphyloenterotoxemia, syphilis, cholera, ehrlichiosis, melioidosis, tuberculosis, tularemia, plague, Q fever, shigellosis, Lyme disease, relapsing fever, spirillary rat-bite fever, streptobacillary rat-bite fever, Borrelia miyamotoi disease
Subtypes (5): typhoid fever, Salmonella gastroenteritis, invasive non-typhoidal salmonellosis, paratyphoid fever, salmonella discitis
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 10.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 6 |
| PHASE2 | 2 |
| PHASE3 | 1 |
| PHASE1/PHASE2 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT01608815 | PHASE3 | COMPLETED | Study of a Single Dose of SP093 Typhoid Vi Polysaccharide Vaccine in Japanese Subjects |
| NCT06213506 | PHASE2 | ACTIVE_NOT_RECRUITING | A Study on the Safety, Reactogenicity, and Immune Response to the GVGH iNTS-GMMA Vaccine Against Invasive Nontyphoidal Salmonella in Adults, Children, and Infants |
| NCT07286370 | PHASE2 | RECRUITING | A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella Disease and Typhoid Fever in Infants |
| NCT05480800 | PHASE1/PHASE2 | COMPLETED | A Study to Evaluate Safety, Reactogenicity, and Immune Response of GVGH iNTS-TCV Vaccine Against Invasive Nontyphoidal Salmonella and Typhoid Fever |
| NCT04694235 | Not specified | ACTIVE_NOT_RECRUITING | Egg Intervention During Pregnancy in Indonesia |
| NCT05870150 | Not specified | ACTIVE_NOT_RECRUITING | Challenge Non-Typhoidal Salmonella (CHANTS) Study |
| NCT00002052 | Not specified | COMPLETED | Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients |
| NCT00177658 | Not specified | COMPLETED | NCCLS Interpretive Criteria for Salmonella |
| NCT02689193 | Not specified | COMPLETED | IDIS Project Work Package 2: Establishing a Biobank at ITM and Collaborating Centres |
| NCT03073707 | Not specified | COMPLETED | Reservoir of Invasive Salmonellosis in Children, DRC |