Sciatic neuropathy

Summary

Sciatic neuropathy (MONDO:0006960) is a disease and 3 clinical trials. A subtype of mononeuropathy — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	sciatic neuropathy
Mondo ID	MONDO:0006960
EFO	EFO:1001166
MeSH	D020426
DOID	DOID:11446
SNOMED CT	52585001
UMLS	C0149940
MedGen	57705
MedDRA	10048950
Is cancer (heuristic)	no

Disease family

This is a subtype of mononeuropathy. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › nervous system disorder › peripheral nervous system disorder › peripheral neuropathy › mononeuropathy › sciatic neuropathy

Related subtypes (6): radial neuropathy, mononeuritis simplex, peroneal neuropathy, femoral neuropathy, tibial neuropathy, ulnar neuropathy

Subtypes (2): lesion of sciatic nerve, sciatica

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06536829	Not specified	RECRUITING	Effects of Myofacial Release Technique and Sciatic Nerve Slider Technique in Sciatica
NCT00934284	Not specified	COMPLETED	Effectiveness Study of Physical Therapy as an Adjunct to a Lumbar Therapeutic Selective Nerve Root Block
NCT01394822	Not specified	COMPLETED	Neuromuscular Ultrasound for Focal Neuropathies