Sigmoid neoplasm
diseaseOn this page
Also known as neoplasm of sigmoid colonsigmoid colon neoplasmsigmoid colon neoplasm (disease)sigmoid colon tumorsigmoid colon tumourtumor of sigmoid colontumour of sigmoid colon
Summary
Sigmoid neoplasm (MONDO:0006971) is a cancer and 4 clinical trials. A subtype of colonic neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).
At a glance
- Classification: Cancer
- Clinical trials: 4
Clinical features
No curated clinical features (Orphanet) for this disease.
Identifiers
Disease identifiers
| Field | Value |
|---|---|
| Canonical name | sigmoid neoplasm |
| Mondo ID | MONDO:0006971 |
| EFO | EFO:1001181 |
| MeSH | D012811 |
| DOID | DOID:1896 |
| SNOMED CT | 126845000 |
| UMLS | C0037073 |
| MedGen | 20753 |
| MedDRA | 10026456 |
| Anatomy (UBERON) | UBERON:0001159 |
| Is cancer (heuristic) | yes |
Also known as: neoplasm of sigmoid colon · sigmoid colon neoplasm · sigmoid colon neoplasm (disease) · sigmoid colon tumor · sigmoid colon tumour · tumor of sigmoid colon · tumour of sigmoid colon
Disease family
This is a subtype of colonic neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.
Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › large intestine disorder › colonic disorder › colonic neoplasm › sigmoid neoplasm
Related subtypes (7): benign colon neoplasm, colon neuroendocrine neoplasm, cecal neoplasm, colon inflammatory polyp, colon juvenile polyp, malignant colon neoplasm, epithelial tumor of colon
Subtypes (2): sigmoid colon cancer, rectosigmoid junction neoplasm
Genetics & variants
GWAS landscape
No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.
Variant details and genetic-evidence tiers
No tiered GWAS variants or ClinVar records for this disease.
Genes & proteins
No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).
Function
No pathway enrichment — requires an associated-gene cohort.
Therapeutics
No druggable-target or therapeutic data for this disease’s cohort.
Clinical trials & evidence
Clinical trials
Clinical trials: 4.
Phase distribution (across all retrieved trials)
| Phase | Trials |
|---|---|
| Not specified | 3 |
| PHASE4 | 1 |
Top trials by phase / activity
| NCT | Phase | Status | Title |
|---|---|---|---|
| NCT05068180 | PHASE4 | UNKNOWN | Low-dose Neuroleptanalgesia for Postoperative Delirium in Elderly Patients |
| NCT03774134 | Not specified | ACTIVE_NOT_RECRUITING | Five Year Oncological Outcome After CME for Sigmoid Colon Cancer |
| NCT01127425 | Not specified | TERMINATED | Length of Hospital Stay, Nursing Hours and Recovery After Laparoscopic Versus Open Colon Resection Without Fast Track |
| NCT07385898 | Not specified | COMPLETED | Effect of Dexmedetomidine on Lung Protection in Elderly Patients Undergoing Laparoscopic Surgery for Colorectal Cancer |
Related Atlas pages
No linked Atlas pages yet — the cross-entity mesh grows as the corpus expands.