Signet ring cell breast carcinoma

Summary

Signet ring cell breast carcinoma (MONDO:0002671) is a cancer. A subtype of breast adenocarcinoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	signet ring cell breast carcinoma
Mondo ID	MONDO:0002671
DOID	DOID:3503
NCIT	C5175
UMLS	C1335964
MedGen	236816
Anatomy (UBERON)	UBERON:0000310
Is cancer (heuristic)	yes

Also known as: breast carcinoma with signet ring · breast signet ring cell carcinoma · mammary signet Ring cell carcinoma · primary mammary signet Ring cell carcinoma · primary signet Ring cell breast carcinoma · primary signet Ring cell carcinoma of breast · primary signet Ring cell carcinoma of the breast · primary SRC breast carcinoma · primary SRC carcinoma of breast · primary SRC carcinoma of the breast · signet Ring cell breast carcinoma · signet Ring cell carcinoma of breast · signet Ring cell carcinoma of the breast · SRC breast carcinoma · SRC carcinoma of breast · SRC carcinoma of the breast

Disease family

This is a subtype of breast adenocarcinoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › integumentary system disorder › integumentary system cancer › breast adenocarcinoma › signet ring cell breast carcinoma

Related subtypes (12): breast lobular carcinoma, mammary Paget disease, breast mucinous cystadenocarcinoma, mucoepidermoid breast carcinoma, adenoid cystic breast carcinoma, sebaceous breast carcinoma, oncocytic breast carcinoma, breast malignant eccrine spiradenoma, breast ductal adenocarcinoma, lobular breast carcinoma in situ, mixed lobular and ductal breast carcinoma, inflammatory breast carcinoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.