Skull base meningioma

Summary

Skull base meningioma (MONDO:0002998) is a disease (an umbrella term covering 10 Mondo subtypes) and 3 clinical trials. A subtype of skull base neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Umbrella term: 10 Mondo subtypes
• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	skull base meningioma
Mondo ID	MONDO:0002998
DOID	DOID:4437
NCIT	C5272
UMLS	C1335976
MedGen	233449
GARD	0023319
Anatomy (UBERON)	UBERON:0002517
Is cancer (heuristic)	no

Also known as: basicranium meningioma (disease) · meningioma (disease) of basicranium · meningioma of the skull base · skull base meningioma

Disease family

This is a subtype of skull base neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › head and neck neoplasm › skull neoplasm › skull base neoplasm › skull base meningioma

Related subtypes (4): sella turcica neoplasm, skull base chordoma, sphenoidal sinus neoplasm, jugulotympanic paraganglioma

Subtypes (10): cavernous sinus meningioma, foramen magnum meningioma, clivus meningioma, multiple skull base meningioma, diaphragma sellae meningioma, suprasellar meningioma, petroclival meningioma, sphenoorbital meningioma, sphenocavernous meningioma, pituitary stalk meningioma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3

Top trials by phase / activity

NCT	Phase	Status	Title
NCT04635657	Not specified	RECRUITING	Cognitive Status After Removal of Skull Base Meningioma
NCT01795300	Not specified	WITHDRAWN	Comparison of Proton and Carbon Ion Radiotherapy With Advanced Photon Radiotherapy in Skull Base Meningiomas: The PINOCCHIO Trial.
NCT06319664	Not specified	COMPLETED	Clinical Outcomes and Decision-making Choice of Skull Base Approaches for Petroclival Meningiomas