Small intestinal intraepithelial neoplasia

Summary

Small intestinal intraepithelial neoplasia (MONDO:0006419) is a disease. A subtype of small intestine neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	small intestinal intraepithelial neoplasia
Mondo ID	MONDO:0006419
NCIT	C27462
UMLS	C1335999
MedGen	236822
Anatomy (UBERON)	UBERON:0002108
Is cancer (heuristic)	no

Also known as: small intestinal dysplasia · small intestinal intraepithelial neoplasia

Disease family

This is a subtype of small intestine neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › intestinal neoplasm › small intestine neoplasm › small intestinal intraepithelial neoplasia

Related subtypes (8): small intestine cancer, jejunal neoplasm, ileal neoplasm, mesenchymal tumor of small intestine, small intestine neuroendocrine neoplasm, adenoma of small intestine, tumor of duodenum, benign neoplasm of small intestine

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.