Small intestine neoplasm

Summary

Small intestine neoplasm (MONDO:0004251) is a cancer (an umbrella term covering 9 Mondo subtypes) and 4 clinical trials. Top therapeutic interventions include nivolumab. A subtype of intestinal neoplasm — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Classification: Cancer
• Umbrella term: 9 Mondo subtypes
• Clinical trials: 4

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	small intestine neoplasm
Mondo ID	MONDO:0004251
DOID	DOID:7505
NCIT	C4432
SNOMED CT	126832004
UMLS	C0345832
MedGen	91055
Anatomy (UBERON)	UBERON:0002108
Is cancer (heuristic)	yes

Also known as: neoplasm of small bowel · neoplasm of small intestine · neoplasm of the small bowel · neoplasm of the small intestine · small bowel neoplasm · small bowel tumor · small bowel tumour · small intestinal neoplasm · small intestine neoplasm · small intestine neoplasm (disease) · small intestine tumor · small intestine tumour · tumor of small bowel · tumor of small intestine · tumor of the small bowel · tumor of the small intestine · tumour of small bowel · tumour of small intestine · tumour of the small bowel · tumour of the small intestine

Disease family

This is a subtype of intestinal neoplasm. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › digestive system disorder › intestinal disorder › intestinal neoplasm › small intestine neoplasm

Related subtypes (5): intestinal neuroendocrine neoplasm, intestinal benign neoplasm, colorectal neoplasm, intestinal cancer, epithelial tumor of anal canal

Subtypes (9): small intestine cancer, jejunal neoplasm, small intestinal intraepithelial neoplasia, ileal neoplasm, mesenchymal tumor of small intestine, small intestine neuroendocrine neoplasm, adenoma of small intestine, tumor of duodenum, benign neoplasm of small intestine

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 4.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3
PHASE2	1

Top trials by phase / activity

NCT	Phase	Status	Title
NCT06638931	PHASE2	RECRUITING	Agnostic Therapy in Rare Solid Tumors
NCT03817866	Not specified	COMPLETED	Chromogranin A as Blood Marker in Cancer Patients
NCT04811833	Not specified	WITHDRAWN	Gastrointestinal Anastomosis Using MonoPlus® Suture
NCT05228379	Not specified	COMPLETED	Small Bowel Capsule Endoscopy: Experience From a Single Large Tertiary Care Centre

Drugs tested across these trials (top 30)

Molecule	Max phase	Trials referencing
NIVOLUMAB	4	1