Spermatic cord torsion

Summary

Spermatic cord torsion (MONDO:0008541) is a disease and 10 clinical trials. A subtype of testicular disorder — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 10

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	spermatic cord torsion
Mondo ID	MONDO:0008541
MeSH	D013086
OMIM	187400
DOID	DOID:11996
ICD-10-CM	N44.0
NCIT	C26885
SNOMED CT	81996005
UMLS	C0037856
MedGen	52446
Is cancer (heuristic)	no

Also known as: testicular torsion · torsion of testis

Disease family

This is a subtype of testicular disorder. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › reproductive system disorder › gonadal disorder › testicular disorder › spermatic cord torsion

Related subtypes (7): chylocele of tunica vaginalis, atrophy of testis, testicular infarct, testicular dysgenesis syndrome, orchitis, neoplasm of testis, acquired testicular failure

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 10.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	10

Top trials by phase / activity

NCT	Phase	Status	Title
NCT05097820	Not specified	RECRUITING	Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants
NCT07133243	Not specified	NOT_YET_RECRUITING	Testicular Torsion Evaluation by ultraSonography Technic Imaging
NCT07301086	Not specified	NOT_YET_RECRUITING	Deep Learning-Assisted Ultrasonic Diagnosis and Localization of Testicular Appendix Torsion
NCT07499024	Not specified	RECRUITING	Evaluation of the Diagnostic Performance of the Testicular Workup for Ischemia and Suspected Torsion (TWIST) Score for Assessing the Risk of Testicular Torsion in Adult Patients Presenting to the Emergency Department With Scrotal Pain - A Prospective Observational Study
NCT07548086	Not specified	NOT_YET_RECRUITING	Light-Based Monitoring (SR-NIRS) for Suspected Testicular Torsion in Children
NCT07554313	Not specified	RECRUITING	Analysis of Factors Associated With Delayed Medical Consultation for Testicular Torsion Among Adolescents in the Haut-Rhin Department Between 2020 and 2025
NCT01812109	Not specified	COMPLETED	Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion
NCT02304575	Not specified	UNKNOWN	Quality of Life Among Testicular Cancer Survivors
NCT04137965	Not specified	UNKNOWN	Testicular Function After Testicular Torsion
NCT05769244	Not specified	COMPLETED	Near Infrared Spectroscopy and Testicular Torsion in Children