Spinal chordoma

Summary

Spinal chordoma (MONDO:0002894) is a disease and 3 clinical trials. A subtype of chordoma — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

• Clinical trials: 3

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	spinal chordoma
Mondo ID	MONDO:0002894
EFO	EFO:1000543
DOID	DOID:4153
NCIT	C5156
UMLS	C1859101
MedGen	347800
GARD	0023291
Is cancer (heuristic)	no

Also known as: chordoma of spinal column · chordoma of spine · chordoma of the spinal column · spinal chordoma · spinal Chordomas · spinal column chordoma

Data availability: 2 cell lines.

Disease family

This is a subtype of chordoma. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › embryonal neoplasm › notochordal tumor › chordoma › spinal chordoma

Related subtypes (3): skull base chordoma, chondroid chordoma, poorly differentiated chordoma

Subtypes (1): sacrum chordoma

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 3.

Phase distribution (across all retrieved trials)

Phase	Trials
Not specified	3

Top trials by phase / activity

NCT	Phase	Status	Title
NCT01346124	Not specified	ACTIVE_NOT_RECRUITING	High Dose Intensity Modulated Proton Radiation Treatment +/- Surgical Resection of Sarcomas of the Spine, Sacrum and Base of Skull
NCT06463262	Not specified	RECRUITING	Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma
NCT05707767	Not specified	UNKNOWN	A Prospective Study of Surgical Treatment Strategies for Chordoma