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Atlas / Disease / Spinal cord cancer

Spinal cord cancer

disease
On this page

Also known as cancer of spinal cordintraspinal tumorintraspinal tumourmalignant neoplasm of spinal cordmalignant neoplasm of the spinal cordmalignant spinal cord neoplasmmalignant spinal cord tumormalignant spinal cord tumourmalignant tumor of spinal cordmalignant tumor of the spinal cordmalignant tumour of spinal cordmalignant tumour of the spinal cordspinal cord neoplasmspine cancertumor of the spinal cordtumour of the spinal cord

Summary

Spinal cord cancer (MONDO:0003544) is a cancer (an umbrella term covering 8 Mondo subtypes) and 20 clinical trials. Top therapeutic interventions include esketamine, lomustine, and pregabalin. A subtype of central nervous system cancer — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

At a glance

  • Classification: Cancer
  • Umbrella term: 8 Mondo subtypes
  • Clinical trials: 20

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

FieldValue
Canonical namespinal cord cancer
Mondo IDMONDO:0003544
DOIDDOID:5612
ICD-10-CMC72.0
ICD-11492029077
NCITC3572
SNOMED CT363475005
UMLSC0153646
MedGen56317
GARD0027641
Anatomy (UBERON)UBERON:0002240
Is cancer (heuristic)yes

Also known as: cancer of spinal cord · intraspinal tumor · intraspinal tumour · malignant neoplasm of spinal cord · malignant neoplasm of the spinal cord · malignant spinal cord neoplasm · malignant spinal cord tumor · malignant spinal cord tumour · malignant tumor of spinal cord · malignant tumor of the spinal cord · malignant tumour of spinal cord · malignant tumour of the spinal cord · spinal cord cancer · spinal cord neoplasm · spine cancer · tumor of the spinal cord · tumour of the spinal cord

Disease family

This is a subtype of central nervous system cancer. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by etiologic mechanism › cancer or benign tumor › neoplastic disease or syndrome › neoplasm › cancer › nervous system cancer › central nervous system cancer › spinal cord cancer

Related subtypes (19): central nervous system primitive neuroectodermal neoplasm, brain cancer, central nervous system sarcoma, primary central nervous system lymphoma, central nervous system germinoma, central nervous system melanocytic neoplasm, central nervous system endodermal sinus tumor, malignant carotid body paraganglioma, malignant adrenal gland pheochromocytoma, malignant jugulotympanic paraganglioma, pheochromocytoma/paraganglioma syndrome 2, pheochromocytoma/paraganglioma syndrome 5, central nervous system Ewing sarcoma/peripheral primitive neuroectodermal tumor, choriocarcinoma of the central nervous system, mixed germ cell tumor of central nervous system, embryonal carcinoma of the central nervous system, malignant tumor of meninges, malignant central nervous system mesenchymal, non-meningothelial neoplasm, malignant glioma

Subtypes (8): spinal cord lymphoma, spinal cord melanoma, spinal cord sarcoma, spinal cord glioma, spinal cord neuroblastoma, spinal meninges cancer, spinal cord primitive neuroectodermal tumor, metastatic malignant neoplasm in the spinal cord

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 20.

Phase distribution (across all retrieved trials)

PhaseTrials
Not specified16
PHASE2/PHASE31
PHASE31
PHASE21
PHASE1/PHASE21

Top trials by phase / activity

NCTPhaseStatusTitle
NCT05096468PHASE2/PHASE3COMPLETEDEsketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.
NCT05493228PHASE3UNKNOWNDexmedetomidine Infusion on Intraoperative Propofol,Fentanyl Requirements in Spine Surgery for Pediatric Cancer Patients
NCT00100802PHASE2COMPLETEDRadiation Therapy, Temozolomide, and Lomustine in Treating Young Patients With Newly Diagnosed Gliomas
NCT00185666PHASE1/PHASE2COMPLETEDCyberknife Precision Radiation Delivery System for Tumors of the Spine
NCT05179824Not specifiedACTIVE_NOT_RECRUITINGTempus Priority Study: A Pan-tumor Observational Study
NCT06042946Not specifiedRECRUITINGMicrosurgical Resection of Intramedullary Spinal Cord Metastases
NCT07056023Not specifiedRECRUITINGMulticenter Trial on Surgical Outcome and Quality of Life in Juxta-medullary Tumors
NCT07066475Not specifiedRECRUITINGA Registry-Based Cohort Study on the Clinical Outcomes of Spinal Cord Glioma Resection Via the Dorsolateral Sulcus Approach
NCT07225491Not specifiedRECRUITINGSpine Oncology Registry
NCT07488702Not specifiedACTIVE_NOT_RECRUITINGIntradurale Spinal Tumors: Management and Treatment
NCT00974623Not specifiedTERMINATEDBone Graft Materials Observational Registry
NCT02494622Not specifiedCOMPLETEDAlternative Treatment of Giant Spinal Schwannomas
NCT02603874Not specifiedUNKNOWNThe Development of a Vertebra Localizing Aid Medical Device
NCT02851706Not specifiedCOMPLETEDNatural History of and Specimen Banking for People With Tumors of the Central Nervous System
NCT03050203Not specifiedCOMPLETEDCustom Pack in Spine Surgery
NCT03593330Not specifiedTERMINATEDNeurosurgical Transitional Care Programme
NCT04219969Not specifiedCOMPLETEDFDG PET-MRI for the Diagnosis of Spinal Cord Lesions
NCT04227717Not specifiedCOMPLETEDStudying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine
NCT04533919Not specifiedWITHDRAWNValidation of Pre-clinical Nano-Based Analgesics in Cells From Human Dorsal Root Ganglia
NCT04957056Not specifiedUNKNOWNFinite Element Study of Biomechanical Changes After Unilateral Hemilamina and Facet Joint Resection of Cervical Spine

Drugs tested across these trials (top 30)

MoleculeMax phaseTrials referencing
ESKETAMINE41
LOMUSTINE41
PREGABALIN41

About this page

Generated deterministically by Sugi Atlas from primary biomedical databases via BioBTree. Every record on this page traces to a primary source.

Generated
Atlas version
v1.1.2
BioBTree
v2.0.2

Sources 24

This page pulls from 24 datasets indexed by BioBTree:

chembl_moleculecivic_evidenceclinical_trialsclinvardoidefogardgenccgwasgwas_studyhgncicd10cmicd11medgenmeshmimmondomondochildmondoparentncitorphanetsctiduberonumls