Sporadic idiopathic steroid-resistant nephrotic syndrome

Summary

Sporadic idiopathic steroid-resistant nephrotic syndrome (MONDO:0019401) is a disease. A subtype of idiopathic nephrotic syndrome — broader associated-gene and molecular evidence is on the parent page (see Disease family below).

Clinical features

No curated clinical features (Orphanet) for this disease.

Identifiers

Disease identifiers

Field	Value
Canonical name	sporadic idiopathic steroid-resistant nephrotic syndrome
Mondo ID	MONDO:0019401
Orphanet	84271
SNOMED CT	717191005
UMLS	C4274017
MedGen	897207
GARD	0025136
Is cancer (heuristic)	no

Also known as: sporadic idiopathic nephrosis

Disease family

This is a subtype of idiopathic nephrotic syndrome. Genetic, therapeutic, and trial evidence is largely curated at the broader-term level — see the parent page for the associated-gene cohort and molecular evidence.

Classification path: disease › human disease › disease by body system or component › syndromic disease › nephrotic syndrome › idiopathic nephrotic syndrome › sporadic idiopathic steroid-resistant nephrotic syndrome

Related subtypes (4): familial idiopathic steroid-resistant nephrotic syndrome, idiopathic steroid-sensitive nephrotic syndrome, idiopathic multidrug-resistant nephrotic syndrome, idiopathic steroid-resistant nephrotic syndrome with sensitivity to second-line immunosuppressive therapy

Subtypes (3): sporadic idiopathic steroid-resistant nephrotic syndrome with focal segmental hyalinosis, sporadic idiopathic steroid-resistant nephrotic syndrome with diffuse mesangial sclerosis, sporadic idiopathic steroid-resistant nephrotic syndrome with collapsing glomerulopathy

Genetics & variants

GWAS landscape

No GWAS associations recorded — common-variant (GWAS) studies don’t cover this disease (typical for Mendelian / rare diseases). See the curated gene cohort and Mendelian overlap below.

Variant details and genetic-evidence tiers

No tiered GWAS variants or ClinVar records for this disease.

Genes & proteins

No associated-gene cohort resolved for this disease. Atlas builds the molecular and therapeutic sections — associated genes, protein families, druggability, pathways, interactions, and drug associations — by aggregating over a disease’s associated genes (resolved via GWAS / GenCC / ClinVar / CIViC), and none resolved here. This is expected for antibody-mediated, autoimmune, or otherwise non-gene-defined conditions; the curated evidence for this disease is its clinical features, GWAS susceptibility, and clinical trials (above).

Function

No pathway enrichment — requires an associated-gene cohort.

Therapeutics

No druggable-target or therapeutic data for this disease’s cohort.

Clinical trials & evidence

Clinical trials

Clinical trials: 0.